Example sentences for: isogenic

How can you use “isogenic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To this end, we have examined the global transcriptional response of a human intestinal epithelial cell line, Caco-2, to infection by L. monocytogenes and isogenic mutants which are disrupted in the actA or prfA gene.

  • One hundred and one well-mapped RI strains could in principle be used to generate 5,050 well-defined isogenic and non-inbred RIX genometypes.

  • To this end, we carried out similar 8-hour time courses with an isogenic L. monocytogenes strain deficient in actA (DP-L1942, Δ actA ), which is unable to nucleate actin polymerization and hence has no capacity for intracellular motility and intercellular spread [ 30].

  • This isogenic strain was constructed in the early 1990s [ 26]; the P1 [ 27], BAC [ 11] and WGS DNA libraries [ 1] were made in 1990, 1998 and 1999, respectively.

  • We have previously characterized an experimental system that enables comparative molecular screening and functional evaluation of candidate breast metastasis-related genes in an isogenic background [ 2 ] . Two independent clones of opposing metastatic phenotype were derived from the MDA-MB-435 breast tumor cell line (metasatic M-4A4 and nonmetastatic NM-2C5 cell lines).


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