Example sentences for: isogenic

How can you use “isogenic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The population of Drosophila melanogaster used in our analysis was a set of 98 RILs (recombinant in lines) derived from a cross of two isogenic lines as described in Wayne et al.

  • In addition, a polymorphism in the isogenic strain resulted in an eighth large-scale sequence difference between Releases 2 and 3. This polymorphic tandem duplication consists of more than 30 kb of sequence bounded by hobo and cruiser transposable elements; half of the BACs mapping to this location contain one copy of the repeat and the other half have two.

  • To validate the editing sites, total RNA was isolated from heads from a mixed population of male and female adult flies from the isogenic strain y 1; cn 1 bw 1 sp 1using the Concert™ Cytoplasmic RNA isolation reagent according to the manufacturer's guidelines (Invitrogen).

  • We have previously characterized an experimental system that enables comparative molecular screening and functional evaluation of candidate breast metastasis-related genes in an isogenic background [ 2 ] . Two independent clones of opposing metastatic phenotype were derived from the MDA-MB-435 breast tumor cell line (metasatic M-4A4 and nonmetastatic NM-2C5 cell lines).

  • We validated these 10 sites by gene-specific RT-PCR using RNA isolated from heads of isogenic animals and identified 15 new sites (see legend to Figure 1).


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