Example sentences for: isogenic

How can you use “isogenic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • An isogenic variant of nontypeable H. influenzae deficient in expression in pili showed a marked reduction in the ability to grow as a biofilm.

  • To this end, we carried out similar 8-hour time courses with an isogenic L. monocytogenes strain deficient in actA (DP-L1942, Δ actA ), which is unable to nucleate actin polymerization and hence has no capacity for intracellular motility and intercellular spread [ 30].

  • Strain M37-1 lacks expression of pili as indicated by absence of hemagglutination and absence of a 22 kDa band on SDS-PAGE corresponding to pilin [ 34 ] . In an experiment comparing biofilm formation in 4 duplicate wells, strain M37-1, the pilus deficient variant, yielded an average optical density of 0.204 whereas its isogenic parent strain, M37, yielded an average optical density of 0.884.

  • To assess the potential role of pili in biofilm formation, a variant of a strain of nontypeable H. influenzae which lacks expression of pili was tested for biofilm formation along with its isogenic parent strain.

  • To test this possibility, two groups of six mice were injected with 2 × 10 9cfu of either wild type or an isogenic sagA/pel mutant isolate and the mice observed over a 72 hour period.


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