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Example sentences for: isolates

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Previous studies from our laboratory have consistently demonstrated loss of the SpeB phenotype in S. pyogenes isolates injected in a skin air sac and recovered from the organs of lethally infected mice [ 10 16 ] . This selection was not associated with loss of β-hemolysis but was associated with over-expression of M and M-related proteins, which in turn are predictive of the invasive potential of the organism in a skin infection model [ 16 ] . Based on the phenotypic characteristics of the kidney-recovered variant (β-hemolytic positive, M and M-related protein positive and SpeB negative) we predicted that this variant would be as virulent or more virulent than the wild type organism in the mouse skin infection model.
Nineteen different pXO2 ORF fragments were detected among the 11 Bacillus isolates.
However, it is important to note that although an increase in the number resistant variants within isolates was readily detected by the PEA, clinically-resistant virus did not develop in the immunocompetent mice.
There was also no evidence that these sequences vary within individual C. pneumoniae isolates.
PCR was performed using template DNA from 11 Bacillus isolates that vary in relatedness to B. anthracis with primer sets designed to amplify DNA fragments from 47 different pXO2 ORFs.