Words similar to isoform-specific

Example sentences for: isoform-specific

How can you use “isoform-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:

Three exons (9br, 23a and 48a) are known to be subjected to alternative splicing and these isoforms were also detected at the protein level with isoform-specific antibodies [ 9 10 ] . Four additional alternative transcripts were described (ex29-, ex30-, ex29/30- and the N-isoform) but no further analysis at the protein level was reported [ 11 12 ] . During mutation analysis in the NF1 -gene we disclosed several additional splice variants in which specific exons were skipped and that were also present in fresh lymphocytes of non-affected persons, albeit typically at a low level [ 13 ] . Several other studies also report the existence of lowly expressed splice NF1 variants.
LLWO2F cell extracts (50 ug) were immunoprecipitated with approximately 1 ug of isoform-specific rabbit antiserum to PP1α as previously described [ 38 ] . Immunoprecipitation with 1 ug of normal rabbit serum served as a negative control.
Compartmentation of PKC isoforms has been suggested as a mechanism for targeting selectivity near their physiological substrates [ 9 10 ] . Consistent with this theme of selectivity, work with isoform-specific antibodies demonstrated that PKC isoforms have distinct subcellular locations [ 11 ] .
To further test this hypothesis, immunoprecipitation and western blotting experiments were carried out using PP1 isoform-specific antibodies.
We discuss the potential significance of these different modes of ER interaction with N-CoR in terms of known isoform-specific behaviors.