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Example sentences for: ipl

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These two elements control, respectively, the allele-specific expression of the H19/Igf2/Ins2 gene cluster, and the second gene cluster containing Kcnq1, the antisense transcript Kcnq1ot1, p57 Kip 2/ Cdkn1c, Slc22a1l, Ipl/Tssc3 and possibly additional genes [ 1 2 ] . There is good evidence assigning one border of the overall imprinted region to the DNA immediately downstream of H19 [ 3 ] . However, the other border, which must lie upstream of Ipl is less well-defined [ 4 ] . Here we show evidence for weak imprinting of a gene, Tnfrh1 , which is located upstream of
Ipl in mice, and which encodes a putative decoy receptor in the TNF receptor family.
These genes represent important targets of flavopiridol action as they encode M-phase regulatory kinases (PLK, aurora/IPL1-related kinase, and ckshs2), M-phase checkpoint proteins (CHK1), and chromosome segregation proteins (CENP-E, CENP-F) (Figure 4a).
Ipl is specifically expressed in the placental labyrinth [ 6 7 ] , and this probe gave a strong signal only in RNA from the superficial halves.
Two imprinted genes with placenta-specific expression and function, namely Ipl and Mash2 [ 6 7 18 19 ] are highly conserved.