Words similar to ipns
Example sentences for: ipns
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Similarly, fungi contain several enzymes involved in secondary metabolite biosynthesis, such as IPNS and DAOCS, that are distinctly related to their counterparts in actinomycetes.
Whereas most of these enzymes necessarily use 2-OG as the acidic substrate, IPNS does not bind 2-OG.
The roles of all these conserved residues in catalysis are apparent from the crystal structures of IPNS, clavaminic acid synthase (CAS) and deacetoxycephalosporin C synthase (DAOCS) [ 8, 9, 10].
In the case of the small-molecule dioxygenase (IPNS/EFE) family, a complex web of relationships can be discerned.
The conserved portion of the 2OG-Fe(II) dioxygenase superfamily proteins comprises the core DSBH domain seen in the IPNS, DAOCS and CAS structures [ 8, 9, 10] and part of the amino-terminal α helix that showed considerable variability in both length and sequence between individual families (Figures 1, 2).
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