Example sentences for: iop

How can you use “iop” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Here, we show increased IOP in mice lacking tyrosinase activity compared to otherwise genetically identical pigmented B6 mice.

  • Less obvious abnormalities in ciliary body tissues may also affect IOP by altering the volume or composition of the aqueous humor produced and possibly by altering the drainage structures in a paracrine fashion [ 42 ] . Thus, more subtle metabolic abnormalities in the ciliary body may interact with the iridocorneal angle phenotypic variation and contribute to variability in IOP elevation between human patients.

  • The magnitude of IOP differences between strains and the good reproducibility of readings over time will allow the use of genetic approaches to identify genes that underlie these differences.

  • Second, although D2 and AKXD28 strains demonstrate similar magnitudes of IOP, AKXD28 mice develop more severe and more extensive retinal damage and are more prone to optic nerve head excavation than D2 mice.

  • Although originally named because of their ability to induce bone and cartilage formation [ 15 ] , BMPs are involved in many developmental processes, including cell proliferation and differentiation, apoptosis, and intercellular interactions during morphogenesis [ 16 17 18 19 20 21 22 23 24 25 ] . Members of the bone morphogenetic protein family function in a gene dosage dependent manner during development and participate in ocular development [ 26 27 28 29 ] . Therefore, mutations that alter the level of BMPs or alter the degree of BMP signaling are candidates to contribute to Axenfeld-Rieger syndrome and other conditions involving anterior segment malformation, elevated IOP, and glaucoma.

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