Words similar to iono
Example sentences for: iono
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2 translocation to Golgi and ER in response 10 μM IONO (Fig.
The immunoblots demonstrate that 30 min treatment in 25 ng/ml anisomycin resulted in phosphorylation of p38 in unstimulated MDCK cells and in cells treated with ATP or IONO.
IONO elicited a sustained, supraphysiological [Ca 2+] i increase in cells that was also slightly enhanced by U0126 (Fig.
One explanation for the decrease in AA is that U0126 inhibits [Ca 2+] i mobilization in response to ATP or IONO, thereby preventing translocation of cPLA 2 . In chick ventricular myocytes, inhibition of MEK1/ERK by PD98059 inhibits zinterol-mediated AA release, but also inhibits zinterol-induced stimulation of [Ca 2+] i cycling in electrically stimulated cells [ 33 ] . In MDCK cells, extracellular ATP acts via P 2Y2 receptors to elicit an IP 3 -mediated [Ca 2+] i increase [ 34 ] and IONO acts to increase [Ca 2+] i by permeabilizing cell membranes to Ca 2+.
To investigate this possibility, cells were transfected with a wild-type cPLA 2 fused to EYFP (EYFP-cPLA 2 ) and the distribution of EYFP-cPLA 2 was imaged in response to [Ca 2+] i transients elicited by ATP and sustained [Ca 2+] i elevations elicited by IONO, in the presence and absence of U0126.