Words similar to interruption
Example sentences for: interruption
How can you use “interruption” in a sentence? Here are some example sentences to help you improve your vocabulary:
Prospective safety outcomes in our study are in accordance with reports from a retrospective analysis of 1,290 patients who interrupted treatment at least once (< 3 mo) without an increased risk of HIV-associated morbidity or mortality (with the exception of patients in Center for Disease Control and Prevention stage C during first interruption only) [21].
Forty-two eligible patients from the Jonathan Lax Immune Disorder Clinic in Philadelphia, Pennsylvania, were randomized via sealed envelopes in a 1:1 fashion to a first phase (phase I) of either (1) three successive TIs of 2, 4, and 6 wk, respectively, or (2) maintenance of ART for 40 wk before a final interruption of therapy in both arms (phase II) subject to therapy reinitiation criteria as described below.
Eighteen patients per group resulted in sufficient power (18 for 90%, 13 for 80%) to determine a difference of 4 wk or greater between groups in time to rebound of virus during the open-ended interruption.
The successful use of HAART is limited by drug-related toxicities, high costs, and drug resistance [3], factors which have led to the development of alternative therapeutic strategies, including the use of supervised, or structured, treatment interruption (STI).
Early treatment of acute HIV-1 infection led to normalization of CD4+ T cell counts in most patients (median, 753 cells/mm 3 ; range, 492–986), but the effect of treatment interruption was variable, even in those doing well, as defined by sustained low viral loads.
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