Example sentences for: interruption

How can you use “interruption” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • During treatment interruptions, there was a variable decline in magnitude, and comparisons between responses on the first day of treatment interruption and last day off therapy did not reach statistical significance (first STI, p = 0.72; second, p = 0.12; and third, p = 0.60, respectively).

  • Study-defined criteria for therapy failure of a previously suppressive regimen were met by 4/21 patients in the continuous therapy/single interruption arm (patients S37, S47, S52, and S59) in association with self-reported nonadherence to therapy and detection of resistance mutations in phase I, as listed in Table 2. One patient in the repeated interruptions arm (1/21; patient S56) failed therapy after 20 wk following the third TI by maintaining a viral load between 50 and 999 copies/ml in the presence of previously undetected resistance mutations.

  • One such approach has been termed supervised treatment interruption (STI)—in which HAART is intermittently stopped once viral load has been reduced to a low level, in order to boost natural immunity by brief exposure to virus.

  • HIV-1-specific humoral immunity can also affect viral control after treatment interruption [46], and viral factors including viral fitness [47,48] and infection with multiple viral variants [49] can influence viral set point and the rate of disease progression.

  • Figure 2 shows study design for both arms, with a median follow-up of 41 (41–42) wk during phase I for the continuous therapy/single interruption arm and 42 (30–51) wk for the repeated interruptions arm.


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