Words similar to interruption
Example sentences for: interruption
How can you use “interruption” in a sentence? Here are some example sentences to help you improve your vocabulary:
Prospective safety outcomes in our study are in accordance with reports from a retrospective analysis of 1,290 patients who interrupted treatment at least once (< 3 mo) without an increased risk of HIV-associated morbidity or mortality (with the exception of patients in Center for Disease Control and Prevention stage C during first interruption only) [21].
However, no significant relationship was observed between the augmentation of epitopes targeted during the second and third treatment pauses and the time the study participants were able to remain off therapy in the respective treatment interruption.
In regards to immunological outcomes, a concern associated with interruption of suppressive therapy is the potential for irreversible, viral-mediated CD4 T cell loss leading to disease progression [6,22].
Following reinitiation of therapy after phase II, patients suppressed viral replication to less than 50 copies/ml by a median time of 10 (6–12) wk in both arms, excluding for two patients in the continuous therapy/single interruption arm who elected to stay off ART indefinitely and one patient from the repeated interruptions arm who reported nonadherence following regimen reinitiation yet reached 52 copies/ml before withdrawing from additional follow-up.
Study discontinuation in the repeated interruptions arm was due to protocol violation ( n = 1; patient restarted therapy during interruption out of protocol), loss to follow-up ( n = 1; patient imprisoned), and virological failure during on-therapy period ( n = 1; further discussed below).
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