Words similar to insertional

Example sentences for: insertional

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Although we have not determined the single-nucleotide polymorphism rate between the libraries, we observed four cases of insertional polymorphisms in which BACs contain transposable elements that are absent from the Release 2 WGS assembly; two on the X, a gtwin element in BACR33A08 and a 412 element in BACR29P19; one on chromosome 2, a roo in BACR01K07 and one on chromosome 3, a roo in BACR02C22.
Gene entrapment has provided effective strategies for insertional mutagenesis of mammalian cells in culture.
In Abcg8 , a large insertional polymorphism was identified in exon 13, that resulted in the insertion of 143 nucleotides in the 3'UTR (*2099_2100ins143nt).
Genes identified using enrichment or screening protocols include Rv2962c and Rv2958c (probable glucuronsyl transferases), Rv2220 (glutamine synthetase A1), Rv3913-Rv3914 (thioredoxin, thioredoxin reductase) and Rv2416c ( eis, unknown function) [ 14 15 22 29 ] . By screening insertional mutants of M. smegmatis, Lagier et al [ 30 ] isolated 8 mutants with impaired ability to survive in human peripheral blood monocyte-derived macrophages and identified the M. tuberculosis gene corresponding the mutated M. smegmatis gene for five of them.
Each respective genome possesses insertion elements (IS900, IS1311) at unique loci that could distinctly affect growth difference or other phenotype by insertional mutation.