Words similar to insertional
Example sentences for: insertional
How can you use “insertional” in a sentence? Here are some example sentences to help you improve your vocabulary:
Genes identified using enrichment or screening protocols include Rv2962c and Rv2958c (probable glucuronsyl transferases), Rv2220 (glutamine synthetase A1), Rv3913-Rv3914 (thioredoxin, thioredoxin reductase) and Rv2416c ( eis, unknown function) [ 14 15 22 29 ] . By screening insertional mutants of M. smegmatis, Lagier et al [ 30 ] isolated 8 mutants with impaired ability to survive in human peripheral blood monocyte-derived macrophages and identified the M. tuberculosis gene corresponding the mutated M. smegmatis gene for five of them.
Identifying insertional knock-outs or creating antisense lines for these transcription factor genes and using them for expression profiling with microarrays constructed from the stress cDNA collection will facilitate identification of the targets for these transcription factors.
In Abcg8 , a large insertional polymorphism was identified in exon 13, that resulted in the insertion of 143 nucleotides in the 3'UTR (*2099_2100ins143nt).
The inserted DNA acts as a tag, making cloning of mutated genes very straightforward, although the efficiency of the initial insertional mutagenesis is much lower than that of the chemical mutagenesis used in the 1992–1993 screens.
Although we have not determined the single-nucleotide polymorphism rate between the libraries, we observed four cases of insertional polymorphisms in which BACs contain transposable elements that are absent from the Release 2 WGS assembly; two on the X, a gtwin element in BACR33A08 and a 412 element in BACR29P19; one on chromosome 2, a roo in BACR01K07 and one on chromosome 3, a roo in BACR02C22.
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