Words similar to insertional

Example sentences for: insertional

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Each respective genome possesses insertion elements (IS900, IS1311) at unique loci that could distinctly affect growth difference or other phenotype by insertional mutation.
About ten years ago, Hopkins started to develop insertional mutagenesis in zebrafish (Figure 2).
Gene entrapment has provided effective strategies for insertional mutagenesis of mammalian cells in culture.
Genes identified using enrichment or screening protocols include Rv2962c and Rv2958c (probable glucuronsyl transferases), Rv2220 (glutamine synthetase A1), Rv3913-Rv3914 (thioredoxin, thioredoxin reductase) and Rv2416c ( eis, unknown function) [ 14 15 22 29 ] . By screening insertional mutants of M. smegmatis, Lagier et al [ 30 ] isolated 8 mutants with impaired ability to survive in human peripheral blood monocyte-derived macrophages and identified the M. tuberculosis gene corresponding the mutated M. smegmatis gene for five of them.
The inserted DNA acts as a tag, making cloning of mutated genes very straightforward, although the efficiency of the initial insertional mutagenesis is much lower than that of the chemical mutagenesis used in the 1992–1993 screens.