Example sentences for: insertional

How can you use “insertional” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Identifying insertional knock-outs or creating antisense lines for these transcription factor genes and using them for expression profiling with microarrays constructed from the stress cDNA collection will facilitate identification of the targets for these transcription factors.

  • Although we have not determined the single-nucleotide polymorphism rate between the libraries, we observed four cases of insertional polymorphisms in which BACs contain transposable elements that are absent from the Release 2 WGS assembly; two on the X, a gtwin element in BACR33A08 and a 412 element in BACR29P19; one on chromosome 2, a roo in BACR01K07 and one on chromosome 3, a roo in BACR02C22.

  • Genes identified using enrichment or screening protocols include Rv2962c and Rv2958c (probable glucuronsyl transferases), Rv2220 (glutamine synthetase A1), Rv3913-Rv3914 (thioredoxin, thioredoxin reductase) and Rv2416c ( eis, unknown function) [ 14 15 22 29 ] . By screening insertional mutants of M. smegmatis, Lagier et al [ 30 ] isolated 8 mutants with impaired ability to survive in human peripheral blood monocyte-derived macrophages and identified the M. tuberculosis gene corresponding the mutated M. smegmatis gene for five of them.

  • Each respective genome possesses insertion elements (IS900, IS1311) at unique loci that could distinctly affect growth difference or other phenotype by insertional mutation.

  • Gene entrapment has provided effective strategies for insertional mutagenesis of mammalian cells in culture.

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