Example sentences for: initiation

How can you use “initiation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This applies to the entire process or life cycle of a transaction or event from the initiation and authorization through its final classification in summary records.

  • However, initiation of deoxycoformycin (pentostatin) therapy resulted in a decrease in the size of the aberrant CD7-dim tumor cluster (as well as decreases in the population of normal T-cells), consistent with treatment response.

  • This result, obtained with cells incubated at 25°C, was consistent with localization of LHCPs on envelope membranes in cells immediately after initiation of thylakoid biogenesis at 38°C [ 16 ] . At the higher temperature, not all the newly synthesized LHCPs were incorporated into envelope membranes, and the excess accumulated in cytosolic vacuoles [ 16 17 ] . This evidence for the envelope as the site of initial interaction of LHCPs with Chl was also supported by proliferation of envelope-derived vesicles in dark-grown Chlamydomonas cells exposed to only a few minutes of light [ 18 ] and the lack of thylakoids in a mutant of Arabidopsis deficient in a protein apparently required for formation of vesicles from the inner membrane of the envelope [ 19 ] .

  • In yeast and mammalian cells, GCN2 is a protein that senses amino acid starvation and brings about altered cell physiology in response to such starvation [ 24 25 ] . GCN2 is a protein kinase that phosphorylates the α subunit of the translation initiation factor eIF2 [ 26 ] . The GCN2 protein from yeasts, Drosophila , and mammals is composed of three domains: a pseudokinase domain that may function as a regulatory domain, a kinase domain, and a HisRS domain that shares significant similarity to histidyl-tRNA synthetases [ 27 28 29 30 ] . Studies of yeast GCN2 revealed that the HisRS domain binds uncharged tRNAs that accumulate when cells are starved for amino acids [ 31 32 ] . As a result the kinase domain is activated and phosphorylates eIF2α at Ser51.

  • We previously reported that enteral nutrition initiated within 36 hours of surgery or admission to the ICU reduces the incidence of infectious complications as compared with nutrition delayed for greater than 36 hours [ 8 ] . The time to the initiation of enteral nutrition was significantly shorter in those patients randomly assigned to receive nutrition by the gastric route (-16.


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