Example sentences for: initiates

How can you use “initiates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Eleusis was home to the Sanctuary of Demeter and the Eleusian Mysteries — a series of complex and enigmatic rituals only performed by initiates of the order.

  • After administration of LPS, TNF and other inflammatory mediators are released [ 11 12 ] . Infusion of TNF initiates an inflammatory process leading to a phenotype that is indistinguishable from bacterial sepsis [ 13 14 ] .

  • Mis-regulation of Wnt signaling leads to the development of several human cancers, including colon carcinomas and melanoma [ 1 ] . Canonical Wnt signaling initiates in the binding of a Wnt ligand to its cell surface receptor, members of the frizzled gene family, along with the co-receptor LRP5/6 [ 2 3 ] , leading to changes in the activities of cytoplasmic effectors resulting in the stabilization of beta-catenin protein.

  • Mutational studies provided the initial hints that disruption of the non-covalent clasp between α and β cytoplasmic tails is clearly the event within the structure of the integrin that initiates inside-out signaling.

  • It remains to be seen if the same approaches work on systems where a single master regulatory gene initiates a developmental cascade, or where integration of developmental cues occurs partly at the level of signal transduction.


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