Example sentences for: impaired

How can you use “impaired” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In both sexes the incidence of impaired lipid profile increased significantly ( P < 0.001) relative to chronological age in comparison to adults.

  • In this study, we have shown for the first time that repair of excision wounds in SPARC-null mice is impaired.

  • These signaling events are generally not entirely abrogated and kinetic analyses have revealed that the sustained phases are particularly impaired in the absence of Btk [ 8, 9, 13].

  • The assembly of myosin II monomers into filaments is regulated by phosphorylation of its heavy chains at three threonine residues at the C-terminus of the tail [ 9 10 ] . Dephosphorylation of these threonines is a prerequisite of filament assembly, as confirmed by the phenotypes of a 3xAsp mutant, in which the three threonines are replaced by three aspartate residues (mimicking the phosphorylated state) [ 11 ] . In vitro the 3xAsp myosin II is severely impaired for filament assembly, and in vivo 3xAsp myosin II fails to assemble or localize to the cortical cytoskeleton.

  • 5A, bottom panel, lanes 5 and 6), consistent with the view that the KKTK mutant is more severely impaired in the ability to bind PIP 2 than are the KK and TK mutants.


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