Example sentences for: impaired

How can you use “impaired” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • BCR-induced activation of the ERK and JNK MAPK pathways is impaired in Btk-deficient DT40 cells, but p38 MAPK activation is unaffected [ 9].

  • An RARα clone truncated after amino acid 403 was effective in repressing reporter gene activity and blocking wild type RAR function [ 10 11 ] . A single amino acid change in RARα (G303E) impaired RA binding affinity and significantly reduced reporter gene activity from responsive promoters.

  • Adolescents with BMI exceeding the 85 thpercentile are at increased risk of being classified as having diabetes or impaired fasting glucose.

  • In particular, free radicals may lead to nuclear and mitochondrial DNA damage and mutations, causing diminished proliferative capacity, premature cellular senescence, and impaired mitochondrial function [ 29 30 ] . For the β-cell, one of the most metabolically active cells in the body, mitochondrial function is essential, and diabetes is a prominent feature of many primary disorders of mitochondrial function [ 30 ] .

  • Alternatively, the lysine at codon 219 may be important for proper in vivo RT function such that the advantage conferred by increased AZT resistance does not adequately compensate for impaired RT function.


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