Words similar to impaired

Example sentences for: impaired

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The sensitivity of the selected cutoff point for BMI values at the 85 thpercentile at 13-15 years old for identifying impaired glucose profile at age 35 y was 76.
Furthermore, we have found that combined mutation of Rlk and Itk leads to profound defects in TCR signaling associated with impaired activation of PLC-γ [ 20].
Thus, CAP would be expected to affect one or more steps required for HIV-1 entry into cells, i.e. binding to cellular CD4, to the major HIV-1 coreceptors CXCR4 or CCR5 for X4 and R5 viruses [ 6 ] , respectively, and fusion with cell membranes [ 7 8 9 10 11 12 13 14 15 ] . Results presented here show that CAP pretreated HIV-1 has a reduced capacity to bind to the coreceptors leading to impaired virus infectivity.
This indicates that the improvement due to RU486 is implemented through modest alteration in GC regulation since complete loss of GR function leads to incomplete lung development at birth and impaired survival through atelectasis [ 77 ] . The neural compartment may have been under-protected by RU486 due to partial exclusion by the blood-brain-barrier, while bone and skeletal muscle, tissues exposed to higher levels of RU486, were clearly protected.
These signaling events are generally not entirely abrogated and kinetic analyses have revealed that the sustained phases are particularly impaired in the absence of Btk [ 8, 9, 13].