Words similar to impair
Example sentences for: impair
How can you use “impair” in a sentence? Here are some example sentences to help you improve your vocabulary:
There is a very tight relationship between the potency of activation domains and their stability [ [ 35 36 37 38 ] ]. Activation domains and sequences required for degradation overlap and mutations in the VP16 activation domain which impair its function result in enhanced protein stability [ 35].
1991), whereas a particular disease mutation may only impair the clasp and partially activate the receptor (Peyruchaud et al.
Contingency requirements for resources whose losswould either prevent or significantly impair the agency from performing its mission or would have an adverse impact on the nation.
An accumulation of 4-HNE-conjugated protein has been detected in lesions of aging-related diseases, including Parkinson's disease [ 53 ] and Alzheimer's disease [ 54 ] . It also accumulates in the affected neuronal tissues of experimental animals experiencing brain ischemia [ 55 56 ] and traumatic spinal cord injury [ 57 ] . 4-HNE can impair synaptosomal membrane proteins, glutamate transport and importantly, mitochondrial functions [ 58 59 ] . Evidence indicates that 4-HNE increases neuronal susceptibility to oxidative stress [ 60 ] and serves as a mediator of oxidative stress that leads to neuronal apoptosis [ 61 ] . As indicated in the Introduction, 4-HNE has been implicated in some ocular pathological conditions [ 19 20 ] .
Equally important, gradual impairment of blood flow that nourishes tissues can lead to peripheral vascular disease, increased susceptibility to infection, cognitive decline, frailty, and other changes that impair life quality and longevity.
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