Example sentences for: immunocompromised

How can you use “immunocompromised” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • After transplantation into immunocompromised mice, circulating human insulin and C-peptide derived from the proinsulin precursor were detected when the mice were given glucose.

  • Cryptosporidiosis is caused by a coccidian parasite, Cryptosporidium , which is transmitted in its infective form, the oocyst, by the fecal-oral route [ 1 ] . It causes self-limited, watery diarrhea in immunocompetent individuals but can be severe and life threatening in people with immunosuppressive conditions [ 2 ] . Because of the severe nature of the disease in the immunocompromised, most epidemiologic studies have focussed on people with HIV/AIDS and other immunosuppressed states [ 3 4 5 6 7 8 9 ] . What is known about transmission patterns in the general US population is based on studies undertaken during outbreaks of the disease, usually waterborne [ 10 11 12 13 14 15 16 ] . Even though cryptosporidiosis is a reportable disease, limited data are available on the routes of endemic transmission and on accurate incidence rates of cryptosporidiosis, especially in the immunocompetent population.

  • To examine whether IPCs are similarly responsive to glucose stimulation in vivo, we performed a series of IPC grafting experiments in immunocompromised recipient mice.

  • S. maltophilia is an important pathogen in nosocomial infections of immunocompromised patients suffering from cancer, cystic fibrosis, drug addition, AIDS and in patients with organ transplants and on dialysis [ 30 31 32 ] . This organism is inherently resistant to most antibiotics due to its low outer membrane permeability [ 33 ] and to β-lactam containing antibiotics due to the production of a chromosomally expressed group 2e β-lactamase (L2) and a group 3c β-lactamase (L1) [ 34 35 ] . L1 has been cloned, over-expressed, and partially characterized by kinetic and crystallographic studies [ 36 37 ] . The enzyme exists as a homotetramer of ca. 118 kDa in solution and in the crystalline state.

  • To both accelerate the development of vascular pathology and to deepen the immunocompromised state, these mice were irradiated with a sublethal dose of gamma radiation (300 Rads) at 4 months of age.


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