Example sentences for: immunocompetent

How can you use “immunocompetent” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the US the potential for drinking water to be associated with cryptosporidiosis among immunocompetent persons is relevant since most major known outbreaks of cryptosporidiosis involved transmission through contaminated water [ 10 11 15 16 21 22 23 24 25 26 27 ] . Additionally, other modes of transmission are of interest because of published reports implicating them (such as food, travel, institution-associated, sexual behavior, etc.) [ 1 2 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 ] . This study was undertaken as the first population-based study in the United States of risk factors for endemic cryptosporidiosis in immunocompetent persons.

  • Foodborne outbreaks of cryptosporidiosis in which the vehicle of transmission was identified are few and only one outbreak in Maine was definitively associated with contaminated fresh-pressed apple cider [ 28 ] . Other foodborne outbreaks due to cryptosporidiosis have implicated food handlers [ 29 ] and social events [ 30 31 ] . Person-to-person outbreaks have been better documented, such as those in hospitals [ 32 33 34 35 36 37 ] and day care centers [ 38 39 ] . It is becoming increasingly evident that cryptosporidiosis is one of the multitude of enteric pathogens that is endemic in hospital and day care settings [ 40 41 42 43 ] . Other routes of exposure to Cryptosporidium may be responsible for sporadic disease in the general population such as specific sexual contact with an infected individual [ 44 45 46 ] , travel to endemic countries [ 47 48 49 50 ] , and contact with animals, both domestic and livestock [ 1 2 51 52 ] . Recent studies in Australia have demonstrated that exposure to persons with diarrhea and swimming in public pools rather than consumption of untreated tap water are the sources of community-acquired cryptosporidiosis in that country [ 53 ] . The relative contribution for each of these modes of transmission to the total burden of sporadic cryptosporidiosis among immunocompetent persons continues to be unknown in the U.S.

  • A lack of any documented risk of staphylococcal infections among workers processing and handling wastewater and sewage sludges may reflect the fact that workers are more immunocompetent than the general population, or that adequate epidemiological studies have not been done.

  • Experimental groups included: 1) adult, immunocompetent 129S mice, and 2) adult B6,129S IFN-γR-/- mice, both obtained from Jackson Laboratories (Bar Harbor, MN).

  • Cryptosporidiosis is caused by a coccidian parasite, Cryptosporidium , which is transmitted in its infective form, the oocyst, by the fecal-oral route [ 1 ] . It causes self-limited, watery diarrhea in immunocompetent individuals but can be severe and life threatening in people with immunosuppressive conditions [ 2 ] . Because of the severe nature of the disease in the immunocompromised, most epidemiologic studies have focussed on people with HIV/AIDS and other immunosuppressed states [ 3 4 5 6 7 8 9 ] . What is known about transmission patterns in the general US population is based on studies undertaken during outbreaks of the disease, usually waterborne [ 10 11 12 13 14 15 16 ] . Even though cryptosporidiosis is a reportable disease, limited data are available on the routes of endemic transmission and on accurate incidence rates of cryptosporidiosis, especially in the immunocompetent population.


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