Example sentences for: icm

How can you use “icm” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The rotation variables of the side chains within 3.5 Å of the modified residues were unfixed and the energy of the system was minimized in the internal coordinate space, according to the ICM method [ 26, 29].

  • Oh, well, there's no way of avoiding the names: In my small clot of people dislodged swardward from the pier were Margaret Carlson, ICM agent Esther Newberg and her escort, newsman/artist John Johnson; illustrator/author/director Lane Smith; Buck Henry; Tony Schwartz; ???; ???; ???.

  • The sequences of AChBP, and of the alpha3, alpha4, alpha7, beta2 and beta4 nAChR monomers were aligned using the ICM multiple sequence alignment algorithm that includes the following steps [ 16 10 ] : 1) pairwise alignment using Needleman and Wunsch algorithm modified to use zero end gap penalties (so called ZEGA) [ 15 16 ] . 2) evolutionary tree construction with a "neighbor-joining algorithm" to determine the order of alignment and calculate relative weights of sequences and profiles from the branch lengths [ 17 ] . 3) traverse the tree from top to bottom, aligning the closest sequences or profiles.

  • This rapid docking procedure was followed by a more refined energy minimization of the complex, with a full atom representation of the receptor, and flexible receptor side chains, according to the ICM stochastic global optimization algorithm [ 26, 27] as implemented in the Molsoft ICM 2.7 program [ 17].

  • The ICM program [ 17] was used to perform both receptor modeling and virtual ligand screening.


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