Example sentences for: ici

How can you use “ici” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, ERβ did bind to a fragment that spanned the extreme C-terminus (2322-2453) and did so in a manner that was promoted by E2 and suppressed by ICI, much like the interactions of ERβ with the entire N-CoR nuclear receptor interacting region.

  • Estrogen receptor antagonist, ICI 182,780 completely, and tamoxifen partially reversed the neuroprotective effects of 17β-estradiol using cell death as an end point.

  • ERα enhances AP-1 activity in response to estrogens, [ 28 29 ] but ERβ inhibits AP-1 activity in response to estrogens [ 29 30 31 ] . ERβ also completely suppresses ERα activity at the cyclin D1 promoter and even suppresses the activity of an ERα mutant that is selectively superactive at AP-1 sites and CREs [ 29 ] . Finally, ERβ shows a unique capacity to enhance AP-1 activity in response to selective estrogen receptor modulators (SERMs) such as raloxifene, tamoxifen and ICI 182,780/Faslodex (ICI) [ 30 31 32 ] . Together, these observations suggest that there are fundamental differences in the way that the ERs bind unspecified cofactors that modulate gene expression, and that some of these cofactors must play a role in differential ER activity at AP-1 sites.

  • When a visitor to one of the councils asked, “Qui est-ce qui parle francais ici?”

  • Both ICI 182,780 and tamoxifen alone did not produce neurotoxicity at the above concentrations (Figure 8D).


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