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Example sentences for: icmb
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New base pairs were proposed when a (new) significant covariation was identified with our newer and more sensitive algorithms that were applied to larger sequence alignments containing more inherent variation (see CRW Methods http://www.rna.icmb.utexas.edu/METHODS/for more detail).
With significant increases in the amount of sequences available for the RNAs under study here, improved programs for the analysis of this data, and better web presentation software, we have established a new "Comparative RNA Web" (CRW) Site http://www.rna.icmb.utexas.edu/.
The first major category, Comparative Structure Models http://www.rna.icmb.utexas.edu/CSI/2STR/contains our most recent 16S and 23S rRNA covariation-based structure models, which were adapted from the original Noller & Woese models (16S [ 15 22 ] and 23S [ 19 ] rRNA), and the structure models for 5S rRNA [ 12 ] , tRNA [ 5 6 7 8 9 ] , and the group I [ 32 ] and group II [ 34 ] introns, as determined by others.
We strongly encourage all users to access the Comparative RNA Web Site http://www.rna.icmb.utexas.eduusing its main address, http://www.rna.icmb.utexas.edu/, rather than through specific URLs.
Each RNA structure model presented here is based upon a single reference sequence, chosen as the most representative for that molecule (Table 1); for example, E. coli is the preferred choice as the reference sequence for rRNA (5S, 16S, and 23S), based on the early and continued research on the structure and functions of the ribosome [ 77 78 ] . Each of the six structure models (5S, 16S and 23S rRNA, group I and II introns, and tRNA) in the "Current Structure Models for Reference Organisms" page http://www.rna.icmb.utexas.edu/CSI/2STR/contains six or seven different diagrams for that molecule: Nucleotide, Tentative, Helix Numbering, Schematic, Histogram, Circular, and Matrix of All Possible Helices.
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