Words similar to hypoperfusion
Example sentences for: hypoperfusion
How can you use “hypoperfusion” in a sentence? Here are some example sentences to help you improve your vocabulary:
In those experiments [ 47, 48], severe hemorrhage (45-47 ml/kg versus 30 ml/kg) might have contributed to ischemia/reperfusion injury, leading to persistent mucosal hypoperfusion and elevated tissue P CO 2 -Pa CO 2 gap.
Studies have demonstrated that an increase in veno-arterial P CO 2 gradient could be a reliable marker of tissue hypoperfusion [ 28, 29, 30, 31, 32].
Therefore, early detection of gastrointestinal hypoperfusion and effective treatment may improve clinical outcome.
Maintenance of splanchnic blood flow is important because splanchnic hypoperfusion may play a critical role in the pathogenesis of multiorgan dysfunction syndrome [ 2 3 ] . Mechanical ventilation has been suggested to potentiate the adverse effects of underlying critical illness on splanchnic vasculature and contribute to the development of multiorgan dysfunction syndrome, particularly when 'injurious' ventilatory strategies that produce high end-inspiratory lung volumes are employed [ 3 ] . Experimental studies suggested that mechanical ventilation with considerably high levels of PEEP can lead to splanchnic hypoperfusion and marked reduction in hepatic blood flow [ 4 5 6 ] . Furthermore, PEEP may decrease splanchnic blood flow in patients with no underlying lung disease [ 7 8 ] . Most available evidence regarding the effects of PEEP from animal studies has been extrapolated to humans based on the assumption that the effects of mechanical ventilation on humans and animals are similar.
However, PEEP can be detrimental because it may, particularly at high levels, decrease cardiac output by decreasing the venous return as a result of diminished pressure gradient between the systemic veins and right atrium [ 1 ] , and consequently it may lead to hypoperfusion of vital organs.
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