Example sentences for: hypophosphorylated

How can you use “hypophosphorylated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Upstream of AP-1 transcription factors, RA has been shown to inhibit epidermal growth factor receptor (EGFR) expression [ 14 ] . To determine if hypophosphorylated RARα could inhibit EGFR expression, we examined expression of the growth factor receptor by western blot in control and S77A mutant cells.

  • , by decreasing RARα phosphorylation) and that in the absence of ligand, hypophosphorylated RARα can mimic the molecular and cellular changes associated with retinoid treatment.

  • pRB phosphorylation varies as a function of cell cycle phase; during G 1 the hypophosphorylated form predominates, while the hyperphosphorylated form accumulates during S, G 2 and M phase [ 14 15 16 ] . It is this hypophosphorylated form of pRB present during early and mid G 1 which functions to modify gene expression.

  • RA is a potent inhibitor of cellular proliferation [ 13 ] . To determine the effects of hypophosphorylated RARα on the growth of human cancer cells, we expressed an S77A RARα expression construct in SCC25 cells.

  • These results indicate that components of the EGFR signaling pathway, upstream of AP-1 transcription factors, are inhibited by hypophosphorylated RARα.


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