Words similar to hypophosphorylated

Example sentences for: hypophosphorylated

How can you use “hypophosphorylated” in a sentence? Here are some example sentences to help you improve your vocabulary:

To confirm that this effect was due to expression of the hypophosphorylated RARα mutant, we also created stable clones expressing either HA tagged RARα or the S77A mutant.
These data suggest that in the unliganded state, hypophosphorylated RARα can mimic the effects of RA on EGFR expression, ERK1 activity, and AP-1 protein levels.
These results indicate that components of the EGFR signaling pathway, upstream of AP-1 transcription factors, are inhibited by hypophosphorylated RARα.
RA is a potent inhibitor of cellular proliferation [ 13 ] . To determine the effects of hypophosphorylated RARα on the growth of human cancer cells, we expressed an S77A RARα expression construct in SCC25 cells.
Under conditions favoring proliferation, the phosphorylation of pRB via cyclin-dependent kinases (CDKs) in mid-to-late G 1 phase results in liberation of E2F and other pRB-bound transcription factors, which then activate the transcription of S-phase genes [ 19 ] . In late M phase, pRB returns to its growth suppressive, hypophosphorylated form due to the action of a pRB-directed protein phosphatase belonging to the type 1 class of serine/threonine protein phosphatases [ 11 20 21 ] .