Words similar to hypophosphorylated
Example sentences for: hypophosphorylated
How can you use “hypophosphorylated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Upstream of AP-1 transcription factors, RA has been shown to inhibit epidermal growth factor receptor (EGFR) expression [ 14 ] . To determine if hypophosphorylated RARα could inhibit EGFR expression, we examined expression of the growth factor receptor by western blot in control and S77A mutant cells.
, by decreasing RARα phosphorylation) and that in the absence of ligand, hypophosphorylated RARα can mimic the molecular and cellular changes associated with retinoid treatment.
pRB phosphorylation varies as a function of cell cycle phase; during G 1 the hypophosphorylated form predominates, while the hyperphosphorylated form accumulates during S, G 2 and M phase [ 14 15 16 ] . It is this hypophosphorylated form of pRB present during early and mid G 1 which functions to modify gene expression.
RA is a potent inhibitor of cellular proliferation [ 13 ] . To determine the effects of hypophosphorylated RARα on the growth of human cancer cells, we expressed an S77A RARα expression construct in SCC25 cells.
These results indicate that components of the EGFR signaling pathway, upstream of AP-1 transcription factors, are inhibited by hypophosphorylated RARα.