Example sentences for: hypophosphorylation

How can you use “hypophosphorylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It is thus conceivable to interpret that the profound inhibition in E2F-1 and PCNA protein levels after 24 h of exposure to 2.5 μM SAHA may result in disintegration and deactivation of D1, E and A cdk2 complexes, which consequently leads to hypophosphorylation of the three Rb pocket proteins.

  • Upon treatment with 2.5 μM SAHA for 24 h, a profound increase in hypophosphorylation of the three pocket proteins was observed in both TM10 and to a lesser extent in TM2H cells as compared with their control counterparts, judged by the faster mobility of the Rb pocket protein isoforms on SDS gel (Fig.

  • SAHA also resulted in the inhibition of G1/S kinase activities and, consequently, hypophosphorylation of the three pRb pocket proteins, which led to G1 cell growth arrest and dramatic decreases in DNA synthesis in both cell lines.

  • To examine whether the increase in hypophosphorylation of pRb2/p130 (Fig.

  • RA inhibited cyclin H and cdk7 expression which correlated with hypophosphorylation of RARα on serine 77.


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