Example sentences for: hypomorphic

How can you use “hypomorphic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • While further analysis might uncover phenotypes associated with this hypomorphic mutation, detailed examination of either cells or mice seemed unjustified in the absence of any greater effect on gene expression.

  • In the case of the Hint-homologous HNT1 gene of S. cerevisiae , the phenotype of the single mutant was mild and the biological pathway, positive regulation of Kin28, the yeast homolog of Cdk7, was revealed by synthetic lethal interactions between hnt1 and hypomorphic alleles of cak1 , kin28 , ccl1 and tfb3 [ 9 ] . Because backup systems to limit problems with hnt2 mutant cells apparently exist, synthetic lethal interactions may be critical to identify the Hnt2 biological pathway.

  • While complete inactivation of SCF Slmbcauses cell death, it was shown that a cell-viable hypomorphic slimb allele resulted in accumulation of unprocessed Ci.

  • To test for the possibility that the proteins encoded by net1(7m) and net1(19m') might be hypomorphic with respect to their resistance toward phosphorylation by Cdc5 (i.e.

  • Therefore it is only rare hypomorphic alleles or allele combinations that allow the animals to survive to adult stage where increased lifespan can be observed.


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