Example sentences for: hydrolysis

How can you use “hydrolysis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Aminoacyl-tRNA synthetases catalyze a succession of reactions, which involve: hydrolysis of the α-β phosphate bond in ATP; condensation of AMP with the cognate amino acid, resulting in the formation of an aminoacyl-adenylate; displacement of the AMP moiety of the aminoacyl-adenylate with the cognate tRNA, producing aminoacyl-tRNA.

  • Although transcription factors bind to specific DNA sequences, the binding activity is not dependent on ATP hydrolysis.

  • In immature B cells, activation through the BCR induces either a state of unresponsiveness, termed anergy, or death by apoptosis, depending on the physical nature and concentration of the antigen [ 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 ] . In some B cell lymphomas, activation through the BCR can induce cell cycle arrest and apoptosis in vitro and tumor dormancy in vivo [ 19 26 27 28 ] . The core of the multi-subunit BCR is membrane-bound immunoglobulin (mIg), which is non-covalently associated with two co-receptor molecules, CD79a (Igα) and CD79b (Igβ), products of the mb-1 and B29 genes [ 29 30 ] . The biochemical changes induced by engagement of the BCR are extensive and include an increase in tyrosine phosphorylation of several intracellular proteins, hydrolysis of membrane phospholipids, fluxes in the concentration of intracellular free Ca 2+, activation of several serine/threonine kinases including components of the MAP kinase pathway, and changes in the activities of a panel of transcription factors.

  • In addition, the minimal kinetic mechanism of nitrocefin hydrolysis by L1 has been reported, and this mechanism predicts that K m does not accurately reflect substrate binding.

  • As we have reported that sCD39 releases intermediate ADP before ADP is further cleaved during ATP hydrolysis [ 25 ] , sCD39 probably has two conformations that bind metal-ADP complexes, one is the conformation that releases the ADP intermediate, and another that recruits intermediate ADP back to the enzyme for further hydrolysis to AMP.


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