Words similar to hydrolases
Example sentences for: hydrolases
How can you use “hydrolases” in a sentence? Here are some example sentences to help you improve your vocabulary:
Two major subfamilies within this family, typified respectively by AcmB and S. aureus LytN, are predominantly restricted to the Gram-positive bacteria, and function as cell-wall hydrolases.
Based on sequence homology, deubiquitinating enzymes were traditionally classified into two families: ubiquitin-specific proteases (UBPs or USPs) and ubiquitin carboxy-terminal hydrolases (UCHs).
Histidine triad (HIT) enzymes are a superfamily of nucleotide hydrolases and transferases that contain a catalytic motif related to the sequence HisφHisφHisφφ (where φ represents a hydrophobic amino acid) and act on substrates containing a nucleoside monophosphate [ 24].
Contrary to this, in the case of the ubiquitin carboxy-terminal hydrolases and the adenoviral proteases there is a tendency for the sheet to be incorporated into a scaffold with other α-helical elements forming a mixed α + β structure.
The human FHIT gene, located at the chromosome 3 fragile site FRA3B, is inactivated early in the development of many tumors [ 1 ] . Murine Fhit is also located at a fragile site [ 2 3 ] and mice heterozygous for disruption of Fhit , given low intragastric doses of the mutagen N-nitrosomethylbenzylamine, develop stomach and sebaceous tumors [ 4 ] that can be prevented by viral Fhit expression [ 5 ] . Fhit, a dimer of 147 amino acid subunits, is a member of the histidine triad (HIT) superfamily of nucleotide hydrolases and transferases [ 6 7 ] . Members of the Hint branch of the HIT superfamily are found in all forms of life [ 8 ] . The S. cerevisiae Hint homolog, Hnt1, and rabbit Hint possess adenosine monophosphoramidase activity that functions in yeast to positively regulate function of Kin28, Ccl1 and Tfb3, which constitute the kinase component of general transcription factor TFIIH [ 9 ] . A new Hint related protein, Aprataxin, is mutated in individuals with ataxia with oculomotor apraxia [ 10 11 ] and has a yeast homolog termed Hnt3 [ 9 ] . Members of the Fhit branch of the HIT superfamily have been found in fungi [ 12 13 ] , animals [ 2 14 15 ] and plants [ 7 ] and hydrolyze diadenosine tetraphosphate, diadenosine triphosphate and other 5'-5"'-dinucleoside polyphosphates.
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