Words similar to hydrolase
Example sentences for: hydrolase
How can you use “hydrolase” in a sentence? Here are some example sentences to help you improve your vocabulary:
S-adenosylhomocysteine (SAH) is the resultant product following the release of a methyl group from s-adenosylmethionine (SAM), a universal methyl donor [ 23 ] . Methyl donation from SAM has crucial developmental impacts governing DNA methylation [ 24 ] as well as methylation of amino acids, proteins, carbohydrates and polysaccharides [ 23 ] . S-adenosylhomocysteine hydrolase is the only known enzyme capable of SAH hydrolysis.
Quantitative analysis of clones of interest, specifically, s-adenosylhomocysteine hydrolase (SAHH), heat shock cognate 70 KD protein (HSC70), and one unknown transcript, OSU-T1-50, were assayed using quantitative real-time RT-PCR [ 14 ] . Individual and small pools of conceptuses were evaluated at the four morphologically distinct stages; spherical (n = 8), ovoid (n = 2), tubular (n = 5) and early filamentous (n = 6).
The resolution of the discordant results for inositol-1,4,5-trisphosphate receptor, H +-ATPase, branched aminotransferase and epoxide hydrolase is presented in Figure 5b.
Human Fhit [ 14 ] and the S. cerevisiae Fhit homolog [ 13 ] , which was called Aph1 but is here termed Hnt2 under nomenclature aproved by the Saccharomyces Genome Database, cleave ApppA more readily while Aph1, the S. pombe homolog, cleaves AppppA more readily [ 20 ] . Consistent with the ApppA hydrolase activity of purified Fhit protein, most cancer cell lines that are Fhit negative at the protein level have higher levels of ApppA than cell lines that are Fhit positive [ 21 ] . Nonetheless, the actual concentrations of dinucleoside polyphosphates were submicromolar in every cell culture sample [ 21 ] and thus, under the reported culture conditions, the measured dinucleoside polyphosphates would not be expected to occupy the Fhit active site substantially [ 19 ] . Dinucleoside polyphosphate levels were measured in adenine-requiring S. cerevisiae strains before or after disruption of the Fhit-homologous HNT2 gene [ 13 ] and in adenine-requiring S. pombe strains as a function of disruption and overexpression of the Fhit-homologous aph1 gene [ 22 ] . Recently, it was observed that diadenosine polyphosphates undergo a divalent cation-dependent conformational change that might mediate their biosynthesis, catabolism or signaling properties [ 23 ] .
Parallel to this, we find that folds with many protein-protein interactions also tend to hold more diverse functions [ 39]; for example, the NTP hydrolase fold is currently associated with nine interdomain interactions within yeast.
Loading...