Words similar to hydrolyze
Example sentences for: hydrolyze
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To combat these enzymes, β-lactamase inhibitors such as clavulanic acid, sulbactam, and tazobactam have been given in combination with a β-lactam containing antibiotic to treat bacterial infections [ 52 ] . One class of β-lactamases that are particularly unaffected by the known β-lactamase inhibitors and have been shown to hydrolyze almost all known β-lactam containing antibiotics including late generation carbapenems at high rates are the metallo-β-lactamases [ 14 15 16 17 18 19 ] . Although there are no reports of metallo-β-lactamases isolated from major pathogens [ 51 53 ] , these enzymes are produced by pathogens such as B. fragilis, S. maltophilia, and P. aeruginosa.
AtPLC1, a protein isolated as a dehydration and salt stress-induced gene, was able to hydrolyze phosphatidylinositol-4,5-bisphosphate and the activity was completely dependent on Ca 2+[ 42].
It is also possible that the site-directed mutants could be utilizing a different mechanism to hydrolyze nitrocefin [ 66 ] .
They hydrolyze the N -acetylmuramate- L-alanine linkage, and are potent bacteriolytic enzymes [ 24, 25].
The APC is a large protein complex that ubiquinates mitotic cyclins and other regulatory proteins that are destined for timely proteolysis by proteasomes [ 10 20 ] . Proteasomes are multicatalytic 26S proteases consisting of a 20S central core catalytic subunit bordered by two 19S components [ 32 33 ] which hydrolyze C-terminal peptide bonds to acidic, basic, and hydrophobic amino-acid residues [ 20 34 ] . Proteasomes proteolyze securins which inhibit separase activity.
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