Example sentences for: hybridoma

How can you use “hybridoma” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • NCAM: A mouse monoclonal antibody raised against the highly sialylated embryonic forms of the neural cell adhesion molecule was used (1:1, Developmental Studies Hybridoma Bank).

  • Additional primary antibodies used were zn-8 to detect Dmgrasp and zrf-1 (Developmental Studies Hybridoma Bank) and polyclonal rabbit anti Pax-2 (Berkeley Antibody Co.).

  • In order to further characterize the biological properties of IROMPs and role of the antibodies produced against them, we raised monoclonal antibodies to the IROMPs by hybridoma technology.

  • Our previous studies of the VH gene repertoire in RA SM [ 13] and studies using a hybridoma approach [ 8] revealed an over-representation of VH4 and a biased set of represented VH4 genes.

  • First, CD4 +T cells selectively proliferate in response to proteoglycan antigens [ 14 ] . Second, prevention of arthritis can be achieved by in vivo treatment with anti-CD4 monoclonal antibodies [ 15 ] . Third, arthritis can be transferred to naïve BALB/c or severe combined immunodeficient (SCID) mice using T and B cells from arthritic animals [ 16 17 18 ] . Fourth, a proteoglycan-specific T-cell hybridoma (T-helper-1 type) can induce arthritis in BALB/c mice [ 19 ] . Finally, CD4 +T cells from arthritic animals are resistant to activation-induced cell death [ 20 ] . These data suggest a breakdown of peripheral tolerance and accumulation of autoreactive T cells in the periphery.


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