Words similar to htk
Example sentences for: htk
How can you use “htk” in a sentence? Here are some example sentences to help you improve your vocabulary:
Tag levels in rapidly growing polyclonal cell lines appear to be set primarily by transcription [ 11 12 ] . However, as discussed above, Tag levels in clonal cell lines produced with the weak htk promoter and generated from slowly growing primary cells are related to clonality.
Finally, the htk lines here varied significantly in terms of Tag expression potential, and in terms of the rate at which expression decreased as a function of cell density.
This suggests that the LTR is less density regulated than the htk promoter, which is subject to down regulation as the cell cycle lengthens during contact inhibition of growth.
IGFR, [ 29 ] ], and one study used several cell lines and demonstrated distinct effects of the cell genetic background [ 25 ] . Down-regulated genes include bFGF, FGF-2, Topoisomerase II-α, EGFR,, human HDAC1, as well as cell cycle regulatory genes among others [ 30 31 32 33 34 35 36 37 ] . Regions in the bFGF promoter have been identified as associated with density-dependent down-regulation of bFGF [ 31 ] . The IGF-II P3 promoter is down-regulated as a function of cell density, and a 7-base pair sequence has been identified that plays a critical role in this down-regulation [ 32 ] . Neither the MoMuLV LTR or the htk promoters encode this sequence, although both encode a 10-base pair sequence that is identical to the P3 sequence with an insertion of 3 base pairs at position -1081.
We noticed however, that initially slow growing cell lines produced with htk driven gene expression needed to be cloned early to prevent overgrowth of more rapidly growing cells that expressed high levels of Tag.
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