Words similar to htk
Example sentences for: htk
How can you use “htk” in a sentence? Here are some example sentences to help you improve your vocabulary:
Tag levels in rapidly growing polyclonal cell lines appear to be set primarily by transcription [ 11 12 ] . However, as discussed above, Tag levels in clonal cell lines produced with the weak htk promoter and generated from slowly growing primary cells are related to clonality.
This supports the idea that the density independent expression in the htk lines is set by the clone specific effects (e.g.
The data presented here show that LTR driven Tag expressing cell lines either increase Tag during exponential growth despite a progressively increasing G 1 phase and contact inhibition (density) or the levels to not change significantly, whereas those created with the htk promoter show varying degrees of reduced expression, that is consistent in magnitude between experiments, as the cell cycle lengthens.
IGFR, [ 29 ] ], and one study used several cell lines and demonstrated distinct effects of the cell genetic background [ 25 ] . Down-regulated genes include bFGF, FGF-2, Topoisomerase II-α, EGFR,, human HDAC1, as well as cell cycle regulatory genes among others [ 30 31 32 33 34 35 36 37 ] . Regions in the bFGF promoter have been identified as associated with density-dependent down-regulation of bFGF [ 31 ] . The IGF-II P3 promoter is down-regulated as a function of cell density, and a 7-base pair sequence has been identified that plays a critical role in this down-regulation [ 32 ] . Neither the MoMuLV LTR or the htk promoters encode this sequence, although both encode a 10-base pair sequence that is identical to the P3 sequence with an insertion of 3 base pairs at position -1081.
Finally, the htk lines here varied significantly in terms of Tag expression potential, and in terms of the rate at which expression decreased as a function of cell density.
Loading...