Example sentences for: hoxc-

How can you use “hoxc-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • An interesting, albeit preliminary, finding from our gene expression studies is that chondrocytes from Hoxc-8 transgenic animals display gene expression profiles that are indicative for immature chondrocytes, but not totally identical.

  • The structural rigidity of rib cartilage is greatly compromised, fatally interfering with pulmonary function, and vertebral cartilage is so weak that the skeleton often disassembles during skeletal preparation [ 1 ] . These results suggest that Hoxc-8 continues to regulate skeletal development well beyond pattern formation in a tissue-specific manner, presumably by controlling the progression of cells along the chondrocyte differentiation pathway.

  • Yet, even if transgene expression was reduced in culture, the important implication of our results is that the downstream biological effects of at least 6 days of Hoxc-8 overexpression in vivo are reversible.

  • Interestingly, chondrocytes from Hoxc-8 tansgenic animals behaved undistinguishable from control cells under all conditions tested.

  • Greater numbers of prehypertrophic cells are unlikely to account for elevated expression of prehypertrophic cell markers: histological sections from Hoxc-8 transgenic animals show no increase in prehypertrophic cells [ 1 ] , and PTHrP receptor mRNA levels are unchanged in cells from transgenic animals (see Figure 8).


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