Example sentences for: hoxa

How can you use “hoxa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We also found distinct patterns of thymocyte proliferation in the Rag1 -/-and Hoxa3,Pax1 mutants.

  • Hoxa3 +/- Pax1 -/-compound mutants had decreased transcription of both cytokines relative to all other genotypes, including Pax1 -/-single mutants.

  • Our results provide direct genetic evidence for these functions of TECs, by showing that these processes are defective in mutants with a primary TEC differentiation defect (the Hoxa3,Pax1 compound mutants).

  • Cytokines produced by TECs are good candidates for mediating at least some of these changes in thymocyte proliferation and apoptosis in the Hoxa3,Pax1 compound mutants.

  • In the Hoxa3,Pax1 compound mutants, cell-autonomous TEC defects cause a partial block at the DN-DP transition, so thymocytes do progress to DP and SP stages, albeit at reduced frequencies [ 29 ] . TEC defects are seen as early as E12.


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