Example sentences for: hoxa

How can you use “hoxa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, Hoxa3 +/- Pax1 -/-compound mutants were not completely missing either cytokine analyzed, and the magnitude of the decrease was variable between pools.

  • We also analyzed two mutant strains that have either cell-autonomous ( Hoxa3 +/- Pax1 -/-) or non-cell-autonomous ( Rag1 -/-) TEC defects, with blocks at different stages of thymocyte differentiation.

  • It is also possible that some of the differences seen between Hoxa3 +/- Pax1 -/-and cytokine mutant phenotypes reflect different effects of cytokines at fetal and adult stages.

  • A striking example is the complete absence of γδTCR +thymocyte development in IL-7 mutants, in contrast to normal γδTCR +cell development in Hoxa3 +/- Pax1 -/-mutants [ 29 ] , which have dramatically reduced IL-7 levels.

  • We compared fetal and adult wild type mice with Hoxa3,Pax1 compound mutants [ 29 34 ] . We also assayed Rag1 -/-mice, which have defects in TEC development due to arrested thymocyte maturation at the TN3 stage [ 35 ] . We found stage-specific differences in proliferation levels between fetal and adult wild type thymocytes.


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