Words similar to hoxa
Example sentences for: hoxa
How can you use “hoxa” in a sentence? Here are some example sentences to help you improve your vocabulary:
We also found distinct patterns of thymocyte proliferation in the Rag1 -/-and Hoxa3,Pax1 mutants.
Hoxa3 +/- Pax1 -/-compound mutants had decreased transcription of both cytokines relative to all other genotypes, including Pax1 -/-single mutants.
Our results provide direct genetic evidence for these functions of TECs, by showing that these processes are defective in mutants with a primary TEC differentiation defect (the Hoxa3,Pax1 compound mutants).
Cytokines produced by TECs are good candidates for mediating at least some of these changes in thymocyte proliferation and apoptosis in the Hoxa3,Pax1 compound mutants.
In the Hoxa3,Pax1 compound mutants, cell-autonomous TEC defects cause a partial block at the DN-DP transition, so thymocytes do progress to DP and SP stages, albeit at reduced frequencies [ 29 ] . TEC defects are seen as early as E12.
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