Words similar to hoxa

Example sentences for: hoxa

How can you use “hoxa” in a sentence? Here are some example sentences to help you improve your vocabulary:

The reduced expression of these cytokines in Hoxa3 +/- Pax1 -/-compound mutants could be an indirect effect of defective TEC differentiation, or could be direct downstream targets since both Hoxa3 and Pax1 are expressed in fetal thymus [ 54 55 ] . Comparison of the Hoxa3 +/- Pax1 -/-phenotype with those of cytokine mutants do not reveal many similarities [ 30 46 56 57 58 59 60 61 ] , probably because of the simultaneous reductions in multiple cytokines in the Hoxa3 +/- Pax1 -/-mutants.
Our previous analysis reported decreased DP cell number and increased apoptosis in both the pre-DP and DP stages in these mutants [ 29 ] . DP cell numbers in both this and our previous study were decreased 10-fold in the Hoxa3 +/- Pax1 -/-compound mutants.
However, Hoxa3 +/- Pax1 -/-compound mutants were not completely missing either cytokine analyzed, and the magnitude of the decrease was variable between pools.
However, to our surprise the two separated lobes from Hoxa3 +/- Pax1 -/-compound mutants did not always develop in predictable ways.
Our results support a critical role for microenvironment created by TECs in regulating thymocyte proliferation during the TN to DP transition, and show that this function is disrupted in Hoxa3,Pax1 compound mutants.