Example sentences for: hox

How can you use “hox” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This has important implications for the identification of the transcriptional targets of Hox transcription factors.

  • We found the expression of p107 mRNA and Bmp-4 mRNA to be decreased, which, if reflected in reduced protein levels, would be consistent with the phenotype of delayed cartilage maturation in Hox transgenic animals: As Bmp-4 was shown to have a positive effect on hypertrophy and inhibitory effect on proliferation [ 37 38 ] , decreased Bmp-4 expression would be expected to promote chondrocyte proliferation.

  • Whether the elevated Ihh mRNA levels originate from increased expression in cells that make Ihh normally (prehypertrophic and hypertrophic chondrocytes) or from ectopic activation by the Hox transcription factors in proliferating cells, remains to be investigated.

  • In summary, the gene expression profiles of primary chondrocytes from Hoxc-8 transgenic animals display notable differences in the expression of regulators of chondrocyte maturation in a pattern largely consistent with delayed chondrocyte maturation in vivo . These results now allow us to investigate whether any of these molecules is directly regulated by Hox transcription factors in chondrocytes.

  • Hox


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