Example sentences for: homozygotes

How can you use “homozygotes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To give meaning to the notions of resistant and susceptible alleles, we assume d > 1 (RR homozygotes do better than SS homozygotes) and a ≤ b ≤ c (given that one is heterozygous, more R alleles are better).

  • Doherty and Zinkernagel [ 20 ] demonstrated using congenic mice that MHC homozygotes had more vigorous immune responses to lymphocytic choriomeningitis virus (LCMV) than the corresponding homozygotes, but since the pathology of the infection they used is due to the immune response, the enhanced immune response actually resulted in reduced survival.

  • In this case, >90% of homozygotes in the population will be homozygous for a susceptible allele, since the frequency of SS homozygotes is Θ = 0.25, while the frequency of RR homozygotes is Π = 0.025.

  • Specifically, population heterozygote advantage may be observed when resistance is additive (heterozygotes have risks equal to the average of the risks of the corresponding homozygotes), when resistance is recessive, or even when it is underdominant (heterozygotes have higher risk of disease than either corresponding homozygote).

  • To measure the quantitites of direct interest, analyses that compare disease outcomes conditional on the alleles involved, rather than grouped comparisons of heterozygotes to homozygotes, will be more informative.


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