Words similar to homology
Example sentences for: homology
How can you use “homology” in a sentence? Here are some example sentences to help you improve your vocabulary:
For a given gene pair AB (A and B are separate genes and are encoded continuously on the chromosome) in the target genome, the presence of AB in a reference genome is recorded when we detect the presence of either an A'B' or a B'A' gene cluster, where gene A' is a homolog of gene A and gene B' is a homolog of gene B. There are many established methods for detecting homology or orthology, for example, membership in the same COG (Clusters of Orthologous Genes) [ 12].
This can be useful in protein structure homology modeling by highlighting the evolutionary contexts for structural analysis within a protein family [ 36].
A flow chart showing the steps involved in the in silico comparison of the coding region of genes within the two alcohol withdrawal QTLs is shown in Figure 1. The National Center for Biotechnology Information (NCBI)/Mouse Genome Database (MGD) human/mouse homology map and the Celera mouse genome assembly were searched to obtain a list of genes and predicted genes within each QTL.
The plot of the ratio of synonymous/nonsynonymous substitutions (dS/dN) identified five regions where the synonymous substitution rate exceeds the nonsynonymous substitution rate (dS / dN > 1), suggesting that homology in these areas was driven by the need for AA conservation (Figure 2b).
In our studies, the M. smegmatis σ Eprotein has 92% homology with the M. tuberculosis σ Eprotein [ 17 ] . While this suggests that the M. tuberculosis σ Eprotein should be able to interact properly with the M. smegmatis RNA polymerase, it also suggests that the M. smegmatis σ Ehomolog might be able to recognize M. tuberculosis σ E-dependent promoters.
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