Example sentences for: homolog

How can you use “homolog” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This is an ADAM10-homolog known to be a tumor necrosis factor-α (TNFα) convertase [ 21 ] , TNFα produced by Kupffer cells in the liver stimulates production of TNFα, a mitogen for hepatocytes helping to generate new cells needed to rebuild damaged areas of the liver [ 22 ] . Kupffer cells have a significant role as mediators of acute inflammation after CCl 4 treatment; however, they also produce factors that can cause secondary injury in the liver through fibrogenic responses.

  • A homolog of H-rev107 is detectable in the pathogenic bacterium V. cholerae , and phylogenetic analysis suggests that it has been acquired through lateral transfer from a vertebrate source.

  • In particular the CyaB homolog from Ralstonia groups very strongly with the animal versions and appears to be a recent horizontal transfer in this bacterium from the latter clade.

  • The gene product of PTEN ( phosphatase and tensin homolog deleted from chromosome 10) is a lipid phosphatase that reverses the activities of phosphatidylinositol 3-kinase (PI3K) by dephosphorylating the D3 position of its lipid products, phosphatidylinositol-3, 4 bis-phosphate (PtdIns(3,4)P2), phosphatidylinositol-3,5 bis-phosphate (PtdIns(3,5)P2), and 3,4,5-tri-phosphate (PtdIns(3,4,5)P3) [ 2, 3], the elevated levels of which are linked to the transforming ability of PI3K [reviewed in ref.

  • In Drosophila there are 2,207 genes for which there is a homolog within the genome and the two homologs are separated by less than 10 genes.


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