Words similar to histopathologically
Example sentences for: histopathologically
How can you use “histopathologically” in a sentence? Here are some example sentences to help you improve your vocabulary:
Infection of cultured podocytes with replication incompetent HIV-1 demonstrated that HIV-1 gene expression leads to the proliferation and dedifferentiation of the infected podocytes [ 6 7 8 ] , recapitulating the phenotypes observed in HIVAN specimens [ 9 10 ] . Similarly, renal expression of replication incompetent HIV-1 proviral transgenes in mice and rats produces a proliferative renal lesion that is indistiguisable both histopathologically and clinically from human HIVAN [ 11 12 13 14 ] . These observations raise the possibility that HIV-1 gene products may interact with mitogenic pathways in infected renal epithelium to cause aberrant cell-cycle engagement.
Histopathologically, all the 55 surgically-resected gastric specimens were confirmed as adenocarcinoma.
Cyclin D 1 is characterized as the major D-type cyclin controlling G 1 -phase progression in kidney cells, both during normal and abnormal proliferation [ 22 23 ] . To determine whether cyclin D 1 may be active in promoting G 1 → S progression in kidneys expressing HIV-1 genes, we utilized a well-characterized HIV-1 transgenic mouse model (Tg26) of HIVAN [ 11 12 13 ] . Secondary to renal expression of the HIV-1 NL4-3 Δ gag-pol proviral transgene, adolescent Tg26 transgenics develop a progressive, proliferative renal disease marked by podocyte and tubular epithelial hyperplasia that is indistinguishable both clinically and histopathologically from human HIVAN.
As in the case of Wnt-1 TG male mice without Pten mutations, the majority of tumors (14/22) arose in the salivary tissue; only a small number of tumors (2/22) were mammary in origin, and, interestingly, some (6/22) were bilateral or unilateral muzzle tumors of epithelial origin, similar histopathologically to lesions found in mammary and salivary tissues.
The sections of colon biopsies were histopathologically negative for diagnostic pathology.
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