Words similar to histopathologic
Example sentences for: histopathologic
How can you use “histopathologic” in a sentence? Here are some example sentences to help you improve your vocabulary:
It may not be coincidental that BRCA1 -mutant breast cancers are preferentially linked to a 'specific' histopathologic pattern that includes a high S-phase fraction of cells, aneuploidy, and hormone receptor-negative status [ 45].
C) Can lung cancer arise directly from normal bronchial mucosa or are histopathologic intermediates required?
Lymphadenectomies with routine histopathologic evaluation have been performed for staging and regional control of primary cutaneous melanoma, even in cases without clinical evidence of metastasis.
As many as 30% of patients with breast cancer who have undergone curative surgery and show no evidence of locoregional or distant disease still have recurrent disease over 5-10 years [ 1 2 ] . Some of these treatment failures may be attributed to residual disease in the breast or axillary lymph nodes [ 3 ] . The limitation of routine histopathologic examination of the tumor margins and the dissected lymph node specimen is well known [ 4 ] . Contemporary methods of detection, including computed tomography, magnetic resonance imaging, bone scintigraphy and flow cytometry, all have limited sensitivity and specificity [ 5 6 ] . Micrometastases can be found by immunohistochemistry or polymerase chain reaction in 10-30% of the patients previously deemed free of disease by conventional histological methods [ 7 8 ] . The prognostic importance of micrometastases found with these sensitive methods are now being evaluated [ 9 10 11 ] .
An aberrant interaction between lymphocytes and different epithelial tissues has been proposed as a mechanism for the damage seen in different organs in 1° SS [ 36 ] . Since it has been suggested that the target tissue involved in the autoimmune histopathologic lesions of 1°SS might be the epithelium [ 37 ] , it is interesting that the findings in our study point to the association of liver disease with pulmonary and renal abnormalities, all which are characterized by epithelial damage [ 38 39 ] . Epithelial cells have been proposed to be active participants rather than passive targets in the chronic immune response in 1°SS but further studies are needed to establish the role of liver epithelial cells in the pathogenesis of hepatic damage in this disease, including the analysis of HLA expression and cytokine secretion pattern in these cells.
Loading...