Words similar to histones
Example sentences for: histones
How can you use “histones” in a sentence? Here are some example sentences to help you improve your vocabulary:
The proper assembly of basic proteins with nucleic acids, such as occurs in the packaging of histones with DNA to produce chromatin and in the packaging of ribosomal proteins with rRNA to form ribosomes, is a reaction that must be facilitated so as to prevent the aggregation of these oppositely charged groups of molecules.
[ 36 ] ). It has been shown that treatment of cells with phorbol esters leads to accumulation of phosphorylated H3 histones [ 37 ] . Therefore, it seems possible that in LS1034 cells PMA could enhance transcriptional activity of chromatin at promoters of MHCII and/or CIITA genes.
Besides covalent modifications, ATP-dependent enzymes such as the Swi2/Snf2 ATPases and other chaperone-like proteins remodel the chromatin by rearranging the binding pattern of histones and other chromosomal proteins [ 9, 10, 11, 12].
This has clearly been the case for histones and ribosomal RNA genes.
In concert with the unrelated acidic protein N1/N2, which binds histones H3 and H4, they act together and with other factors to assemble nucleosomes [ 2 3 ] . In addition to assembly, nucleoplasmin and other proteins are involved in the chromatin remodeling and nucleosome disassembly that occurs, for example, during transcription to allow the access of transcription factors to nucleosomal DNA [ 4 ] . Another major function of nucleoplasmin is the decondensation of sperm chromatin at fertilization.
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