Example sentences for: histone

How can you use “histone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Human activating transcription factor-2 (ATF-2): a predicted histone acetyltransferase

  • It has been reported that upregulation of KIAA0128 gene expression, which has been implicated in activation of histone mRNA synthesis, was related to cell cycle arrest in MCF-7 cells after treatment with SAHA [ 43].

  • These included histone H4, which did not exhibit differential expression in the two tissues (log 2 ratio around 0); cytochrome oxidase IV, kynurenine 3-hydroxylase, serine/threonine protein kinase and 14-3-3 protein gamma which exhibited two- to threefold differences (log 2 ratio = 1 to 1.6); and desmin which was around 32-fold differentially expressed between the two tissues (log 2 ratio approximately 5).

  • KIAA0601, along with the co-repressor CoREST, is stably associated with the histone deacetylase complex.

  • These data, therefore, suggest that other epigenetic mechanisms involving defects in chromatin modification factors such as acetylation and methylation of histone proteins may also play role in gene silencing.


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