Example sentences for: histone

How can you use “histone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Other epigenetic mechanisms involving defects in chromatin modification factors such as the association of methyl-CpG binding proteins, acetylation and methylation of histone proteins are also becoming known [ 15 ] . The role of these chromatin-mediated components in inactivating the MGMT gene remains to be examined in GCT.

  • Histone acetylation and p53 mutation appear not to be correlated in this study; nevertheless, it is necessary and more sensitive to examine histone acetylase and deacetylase activities in correlation to p53 status.

  • It has been reported that upregulation of KIAA0128 gene expression, which has been implicated in activation of histone mRNA synthesis, was related to cell cycle arrest in MCF-7 cells after treatment with SAHA [ 43].

  • Human activating transcription factor-2 (ATF-2): a predicted histone acetyltransferase

  • Ample studies have demonstrated the implication of histone hyperacetylation in gene transcription but also in silencing gene expression of others [ 27, 44, 45].


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