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Example sentences for: hgec

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Stx-1 (72 hr exposure to toxin) dose-dependently killed HGEN, HGEC and HPT (Figure 1).
HGEN, HGEC and HPT were chosen for examination in this study because these cell types, at least in vitro , have been shown to be injured by Stx-1 [ 6 7 8 ] . Mesangial cells were not examined since Stx-1 has not been demonstrated to affect their viability [ 13 ] . Previous studies have separately examined the cytotoxic effect of Stx-1 on HGEN [ 8 ] , HGEC [ 10 ] , and HPT [ 9 ] , however this is the first study to directly compare Stx-1 sensitivity of these renal cell types.
In HGEN, Stx-1 had an LD50 of about 10 -5g/L (140 pM), while in HGEC the LD 50 for Stx- was about 10-8 g/L (140 fM) and in HPT the LD 50 for Stx was about 10 -9.
Although speculative, it is tempting to propose that HPT and HGEC may be early targets of Stx-1 and that this could play a role in the pathophysiologic processes that characterize renal injury in HUS.
The effect of 1, 2 or 7 days of exposure to physiologic or pharmacologic concentrations of progesterone, estradiol or testosterone on Gb3 expression by HGEN, HGEC or HPT was also examined.