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Example sentences for: hgec

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HGEC human glomerular visceral epithelial cells
Although speculative, it is tempting to propose that HPT and HGEC may be early targets of Stx-1 and that this could play a role in the pathophysiologic processes that characterize renal injury in HUS.
Exposure for 1, 2 or 7 days to high (1 μM) or physiologic concentrations (reference range of physiologic steroid concentrations based on Barnes Hospital Laboratory Manual [ 11 ] ) of progesterone (30 nM), β-estradiol (100 pM), or testosterone (30 nM) had no effect on HGEN (Table 1), HGEC (Table 2) or HPT (Table 3) responsiveness to Stx-1.
HGEN, HGEC and HPT were chosen for examination in this study because these cell types, at least in vitro , have been shown to be injured by Stx-1 [ 6 7 8 ] . Mesangial cells were not examined since Stx-1 has not been demonstrated to affect their viability [ 13 ] . Previous studies have separately examined the cytotoxic effect of Stx-1 on HGEN [ 8 ] , HGEC [ 10 ] , and HPT [ 9 ] , however this is the first study to directly compare Stx-1 sensitivity of these renal cell types.
Primary cultures of HGEC were obtained from nephrectomies as previously described [ 10 ] and studied at the third passage.