Example sentences for: gpiib

How can you use “gpiib” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The genotype data are then merged with the clinical, stroke, and follow-up data and analyzed to ascertain potential associations between stroke risk and genes for β-fibrinogen and platelet GPIa, GPIbα, or GPIIb/III.

  • When platelets aggregate, GPIIb/IIIa binds to fibrinogen and vWF.

  • Thus, we propose to study polymorphisms in genes involved in a number of systems and pathways related to stroke risk [ 5 ] : genes associated with coagulation factors and thrombophilia (Factor V, Prothrombin, Fibrinogen, Factor VII, Factor XIII, PAI-1, Thrombomodulin [TM], and MTHFR), as well as polymorphisms in genes that are involved in vascular reactivity (ACE), platelet activation/function (GpIIb/IIIa, GpIb IX-V, and GpIa/IIa), endothelial cell function (MTHFR, TM, VCAM-1, E-Selectin, L-Selectin, P-Selectin, and ICAM-1), inflammation (TNFα), lipid metabolism (Apo A1 and Apo E), and cell adhesion (VCAM-1, E-Selectin, L-Selectin, P-Selectin, and ICAM-1).

  • The primary aim of ISGS is to test the association between ischemic stroke and the following putative risk factor polymorphisms: β-fibrinogen C148T, G448A, and G455A; GPIa C807T; GPIbα HPA-2 and VNTR; and GPIIb/IIIa P1A.

  • Many receptors are involved in platelet adhesion and many agonists stimulate platelet aggregation, but platelet aggregation requires GPIIb/IIIa.


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