Example sentences for: gpibα

How can you use “gpibα” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus, initial analyses using members of the fibrinogen cluster (or with other candidate genes such as GPIbα) will focus on each case/control being classified by the presence of a risk allele (yes/no), with comparison of SNP allele frequencies between groups (stroke/control).

  • For other candidate genes (GPIbα, etc.), distributions of genotypes or strata determined by alleles or haplotypes can be established for comparison.

  • For example, GPIbα has a series of polymorphisms that may define an allele of interest.

  • One GPIbα polymorphism is referred to as "VNTR" because it consists of a variable number of tandem repeats of 39 base pairs, each repeat leading to a 13-amino acid addition that pushes a vWF-binding domain further away from the platelet membrane surface.

  • The main end point of the study is whether any of the polymorphisms (the β-fibrinogen polymorphisms C148T, G448A, and G455A and the platelet GP polymorphisms GPIa C807T, GPIbα HPA-2 and VNTR, and GPIIb/IIIa P1A) are associated with ischemic stroke.


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