Words similar to gpibα
Example sentences for: gpibα
How can you use “gpibα” in a sentence? Here are some example sentences to help you improve your vocabulary:
For other candidate genes (GPIbα, etc.), distributions of genotypes or strata determined by alleles or haplotypes can be established for comparison.
Thus, initial analyses using members of the fibrinogen cluster (or with other candidate genes such as GPIbα) will focus on each case/control being classified by the presence of a risk allele (yes/no), with comparison of SNP allele frequencies between groups (stroke/control).
The genotype data are then merged with the clinical, stroke, and follow-up data and analyzed to ascertain potential associations between stroke risk and genes for β-fibrinogen and platelet GPIa, GPIbα, or GPIIb/III.
One GPIbα polymorphism is referred to as "VNTR" because it consists of a variable number of tandem repeats of 39 base pairs, each repeat leading to a 13-amino acid addition that pushes a vWF-binding domain further away from the platelet membrane surface.
The main end point of the study is whether any of the polymorphisms (the β-fibrinogen polymorphisms C148T, G448A, and G455A and the platelet GP polymorphisms GPIa C807T, GPIbα HPA-2 and VNTR, and GPIIb/IIIa P1A) are associated with ischemic stroke.