Example sentences for: gpi

How can you use “gpi” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It was shown previously that APN may be purified with intact GPI-anchors if PIPLC is omitted from the preparation buffer [ 6 ] . It is likely that our APN has similarly retained the GPI anchor.

  • It is synthesized as a 69 kDa precursor that is proteolytically processed into a 40 kDa membrane bound form that is glycosylphosphatidylinositol (GPI)-linked and a 32 kDa secreted form.

  • Hyal-2 is found in the lysosome and is active under conditions of low pH [ 20 ] . Hyal-2 is also found on the cell surface as a glycosylphosphatidylinositol (GPI)-anchored receptor for jaagsiekte sheep retrovirus [ 21 ] . Nonetheless, the enzymatic activity of Hyal-2 has not been detected [ 21 ] . Whether the increased TNF cytotoxicity in L929 cells caused by Hyal-1 and Hyal-2 is associated with their enzymatic activities is being studied in this laboratory.

  • There is now compelling evidence demonstrating that CD9, a tetraspan membrane protein, is present on the oolemma and essential for sperm-egg fusion, possibly by organizing functional multimolecular complexes in the egg [ 7 ] . Glycosyl-phophatidyniositol (GPI)-anchored proteins have also been described on the oolemma and implicated in sperm-egg fusion; removal of GPI-anchored protein from the egg plasma membrane results in greatly reduced fertilization rates without affecting sperm-zona pellucida binding [ 8 ] . Other egg surface molecules are the adhesion molecules NCAM, VCAM-1, ICAM-1 and ECAD [ 9 ] , and the selectins [ 10 ] . Additionally, the IgG receptor [ 11 ] , complement receptors C1q [ 12 ] , CD35 and CD11b, [ 13 ] and the Fc gamma receptors [ 14 ] exhibit oolemmal expression in a variety of mammalian species.

  • Bt, Bacillus thuringiensis ; APN, aminopeptidase N; GPI, glycosyl-phosphatidylinositol; BBMV, brush border membrane vesicles; LpNA, leucine-p-nitroanilide; PIPLC, phosphatidylinositol-specific phospholipase C; HBS, Hepes-buffered saline; SPR, surface plasmon resonance


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