Example sentences for: gpi

How can you use “gpi” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Hyal-2 is found in the lysosome and is active under conditions of low pH [ 20 ] . Hyal-2 is also found on the cell surface as a glycosylphosphatidylinositol (GPI)-anchored receptor for jaagsiekte sheep retrovirus [ 21 ] . Nonetheless, the enzymatic activity of Hyal-2 has not been detected [ 21 ] . Whether the increased TNF cytotoxicity in L929 cells caused by Hyal-1 and Hyal-2 is associated with their enzymatic activities is being studied in this laboratory.

  • The Sperm Adhesion Molecule 1 (SPAM1 or PH-20) is a glycosyl-phosphatidylinositol (GPI)-linked protein found on all mammalian spermatozoa that have been examined, and has been reported to play multiple roles in fertilization [ 1 ] . Although a recent gene targeting study indicates that in mice, which have four active non-somatic hyaluronidases, Spam1 is not essential for fertilization [ 2 ] ; this is unlikely to be the case in humans where SPAM1 is the only such hyaluronidase present.

  • It is synthesized as a 69 kDa precursor that is proteolytically processed into a 40 kDa membrane bound form that is glycosylphosphatidylinositol (GPI)-linked and a 32 kDa secreted form.

  • It was shown previously that APN may be purified with intact GPI-anchors if PIPLC is omitted from the preparation buffer [ 6 ] . It is likely that our APN has similarly retained the GPI anchor.

  • GPI: Glycophosphatidylinositol


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