Words similar to gpi
Example sentences for: gpi
How can you use “gpi” in a sentence? Here are some example sentences to help you improve your vocabulary:
It was shown previously that APN may be purified with intact GPI-anchors if PIPLC is omitted from the preparation buffer [ 6 ] . It is likely that our APN has similarly retained the GPI anchor.
It is not known whether the GPI anchor is still intact on the APN receptor; however, in the current study, phosphatidylinositol-specific phospholipase C (PIPLC) was not used during BBMV preparation.
The first toxin-binding receptor purified from B. mori was a 120-kDa aminopeptidase N (APN), which appears around 110-kDa on SDS-PAGE gels when preparative conditions are used that cleave its glycosyl-phosphatidylinositol (GPI) anchor.
There is now compelling evidence demonstrating that CD9, a tetraspan membrane protein, is present on the oolemma and essential for sperm-egg fusion, possibly by organizing functional multimolecular complexes in the egg [ 7 ] . Glycosyl-phophatidyniositol (GPI)-anchored proteins have also been described on the oolemma and implicated in sperm-egg fusion; removal of GPI-anchored protein from the egg plasma membrane results in greatly reduced fertilization rates without affecting sperm-zona pellucida binding [ 8 ] . Other egg surface molecules are the adhesion molecules NCAM, VCAM-1, ICAM-1 and ECAD [ 9 ] , and the selectins [ 10 ] . Additionally, the IgG receptor [ 11 ] , complement receptors C1q [ 12 ] , CD35 and CD11b, [ 13 ] and the Fc gamma receptors [ 14 ] exhibit oolemmal expression in a variety of mammalian species.
Hyal-2 is found in the lysosome and is active under conditions of low pH [ 20 ] . Hyal-2 is also found on the cell surface as a glycosylphosphatidylinositol (GPI)-anchored receptor for jaagsiekte sheep retrovirus [ 21 ] . Nonetheless, the enzymatic activity of Hyal-2 has not been detected [ 21 ] . Whether the increased TNF cytotoxicity in L929 cells caused by Hyal-1 and Hyal-2 is associated with their enzymatic activities is being studied in this laboratory.
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