Words similar to gpi

Example sentences for: gpi

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It is synthesized as a 69 kDa precursor that is proteolytically processed into a 40 kDa membrane bound form that is glycosylphosphatidylinositol (GPI)-linked and a 32 kDa secreted form.
Bt, Bacillus thuringiensis ; APN, aminopeptidase N; GPI, glycosyl-phosphatidylinositol; BBMV, brush border membrane vesicles; LpNA, leucine-p-nitroanilide; PIPLC, phosphatidylinositol-specific phospholipase C; HBS, Hepes-buffered saline; SPR, surface plasmon resonance
The first toxin-binding receptor purified from B. mori was a 120-kDa aminopeptidase N (APN), which appears around 110-kDa on SDS-PAGE gels when preparative conditions are used that cleave its glycosyl-phosphatidylinositol (GPI) anchor.
The Sperm Adhesion Molecule 1 (SPAM1 or PH-20) is a glycosyl-phosphatidylinositol (GPI)-linked protein found on all mammalian spermatozoa that have been examined, and has been reported to play multiple roles in fertilization [ 1 ] . Although a recent gene targeting study indicates that in mice, which have four active non-somatic hyaluronidases, Spam1 is not essential for fertilization [ 2 ] ; this is unlikely to be the case in humans where SPAM1 is the only such hyaluronidase present.
It is not known whether the GPI anchor is still intact on the APN receptor; however, in the current study, phosphatidylinositol-specific phospholipase C (PIPLC) was not used during BBMV preparation.