Words similar to gpcr
Example sentences for: gpcr
How can you use “gpcr” in a sentence? Here are some example sentences to help you improve your vocabulary:
To determine the effect of insulin receptor or IGF-1 receptor activation on GPCR's, cells were treated with insulin or IGF-1.
To our knowledge, this is the first description of MAP kinase regulation of a GPCR and suggests that this form of regulation may be more wide-spread than has been previously recognized.
G protein-coupled receptor (GPCR) kinase-interactor-2 (Fig.
Despite numerous reported differences, it does appear that diverse GPCRs share common mechanistic themes during ERK stimulation, including the tyrosine-phosphorylation of Shc and its complexing with Grb2, mSOS recruitment, the GTP-loading of Ras, and Raf-1 activation leading to MEK-1 phosphorylation [ 1 ] . However, the progression of each of these downstream events after GPCR stimulation depends first on the tyrosine phosphorylation of a membrane-bound protein that will be used as a scaffold, which will bind the other proteins (e.g.
Two possibilities have emerged as potential sites of tyrosine phosphorylation and subsequent scaffold building in response to GPCR stimulation, which results in ERK activation: the GPCR, itself, or a co-expressed RTK (i.e.