Example sentences for: gpcr

How can you use “gpcr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Determining the prevalence and specificity of MAP kinase modulation of GPCR's will await future studies.

  • GPCR models for Smo and potential mechanisms of Ptc function

  • G protein-coupled receptor (GPCR) kinase-interactor-2 (Fig.

  • Despite numerous reported differences, it does appear that diverse GPCRs share common mechanistic themes during ERK stimulation, including the tyrosine-phosphorylation of Shc and its complexing with Grb2, mSOS recruitment, the GTP-loading of Ras, and Raf-1 activation leading to MEK-1 phosphorylation [ 1 ] . However, the progression of each of these downstream events after GPCR stimulation depends first on the tyrosine phosphorylation of a membrane-bound protein that will be used as a scaffold, which will bind the other proteins (e.g.

  • , [ 27 ] reported that endogenously-expressed LPA and endothelin-1 (ET-1) receptors in SK-N-MC cells do not activate ERKs unless the EGFR is co-expressed, although each GPCR is functional as evidenced by their ability to increase intracellular [Ca 2+].


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