Example sentences for: gpcr

How can you use “gpcr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • ‘There is a precedent for that’, he claims, noting that extracellular calcium is sensed by a GPCR.

  • Despite numerous reported differences, it does appear that diverse GPCRs share common mechanistic themes during ERK stimulation, including the tyrosine-phosphorylation of Shc and its complexing with Grb2, mSOS recruitment, the GTP-loading of Ras, and Raf-1 activation leading to MEK-1 phosphorylation [ 1 ] . However, the progression of each of these downstream events after GPCR stimulation depends first on the tyrosine phosphorylation of a membrane-bound protein that will be used as a scaffold, which will bind the other proteins (e.g.

  • The 5-HT 2C receptor is a member of the GPCR family.

  • Furthermore, since some GPCRs can modulate MAP kinase activity, MAP kinase regulation of GPCR function may then serve as a form of negative feedback control in much the same way that protein kinase A, protein kinase C and the G protein-coupled receptor kinases (GRKs) regulate GPCRs.

  • Determining the prevalence and specificity of MAP kinase modulation of GPCR's will await future studies.


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