Example sentences for: gpcr

How can you use “gpcr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, there is little evidence for reciprocal regulation: MAP kinase effects on GPCR function.

  • GPCR models for Smo and potential mechanisms of Ptc function

  • It has been postulated that activation of these kinases allows GPCR agonists to modulate such diverse molecular events as cell proliferation, differentiation, and survival [ 1 ] . To date, all three cloned opioid receptor types (μ,δ, κ) and the closely related nociceptin receptor have demonstrated the ability to signal through their heterotrimeric G proteins (G i or G o ) to at least one type of MAPK [ 2 3 4 ] . Among the members of this family that are activated by opioids, are the two extracellular signal-regulated protein kinases (p44 MAPK(ERK 1) and p42 MAPK(ERK 2)) [ 5 ] and the p38 protein kinase [ 3 ] . However, the precise mechanism by which OR stimulation produces an increase in MAPK activity is still unknown and under investigation.

  • C6 glioma cells have been used as host cells for the transfection of several GPCR types, and have the advantage of expressing high levels of ERK, while being devoid of the EGFR.

  • ‘There is a precedent for that’, he claims, noting that extracellular calcium is sensed by a GPCR.


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