Words similar to gpcr
Example sentences for: gpcr
How can you use “gpcr” in a sentence? Here are some example sentences to help you improve your vocabulary:
Despite numerous reported differences, it does appear that diverse GPCRs share common mechanistic themes during ERK stimulation, including the tyrosine-phosphorylation of Shc and its complexing with Grb2, mSOS recruitment, the GTP-loading of Ras, and Raf-1 activation leading to MEK-1 phosphorylation [ 1 ] . However, the progression of each of these downstream events after GPCR stimulation depends first on the tyrosine phosphorylation of a membrane-bound protein that will be used as a scaffold, which will bind the other proteins (e.g.
To our knowledge, this is the first description of MAP kinase regulation of a GPCR and suggests that this form of regulation may be more wide-spread than has been previously recognized.
Determining the prevalence and specificity of MAP kinase modulation of GPCR's will await future studies.
To determine the effect of insulin receptor or IGF-1 receptor activation on GPCR's, cells were treated with insulin or IGF-1.
For the GPCR model, the tyrosine kinase(s) involved and the site of this multi-protein complex formation is less clear.