Words similar to gpc

Example sentences for: gpc

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Each sample was analyzed for exon 2-23 of the SLC15A1 gene (Table 3) and 7 coding fragments of the GPC5 gene (Table 4).
Gene mapping studies using microsatellite markers have identified chromosome 13q32 as one of the putative loci for Schizophrenia and Bipolar disorder [ 10 11 12 13 15 ] . To begin identification of a susceptibility gene for Bipolar disorder, we have screened two candidate genes, SLC15A1 and GPC5, on the basis of their genetic localization within the 10 cM region of chromosome 13q32 [ 14 ] . The entire SLC15A1 gene was represented in one BAC clone sequence AL357553 and GPC5 in 6 BAC clone sequences.
The coding sequence of GPC5 gene is 2558 bp long and encodes 572 amino acids.
While we finished screening this gene for mutations, its genomic structure was published and confirms the presence of 8 exons with exon/intron boundaries following the AG/GT rule with a size of approximately 2 Mb [ 30 ] . No mutations or polymorphisms were identified in the GPC5 gene in the 7 families affected with Bipolar disorder decreasing the likelihood that this gene is involved in the etiology of Bipolar disorder.
Intronic oligonucleotide primer pairs flanking the coding fragments were designed for both the genes using program primer 3 http://www.genome.wi.mit.edu/cgi-bin/primer/primer3.cgiusing the genomic sequences of SLC15A1 and GPC5 gene respectively.