Words similar to gpc
Example sentences for: gpc
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Deletion of the 13q region is associated with human 13q syndrome, a developmental disorder [ 24 ] . Some of the proteoglycans play important functional roles in neurogenesis, axon guidance, synapse development [ 25 ] , and cellular growth and differentiation [ 26 27 23 ] . Mutations in GPC3 cause Simpson-Golabi-Behmel syndrome [ 28 29 ] , however, no mutations were detected in the GPC5 and GPC6 genes [ 30 ] . The glypican1 gene has been suggested to be a good candidate for brachydactyly type E [ 31 ] . Given that, GPC5 is highly expressed in brain and mutations in other genes of the glypican families are associated with developmental disorder; GPC5 could be a potential candidate gene for Bipolar disorder.
Each sample was analyzed for exon 2-23 of the SLC15A1 gene (Table 3) and 7 coding fragments of the GPC5 gene (Table 4).
Exon 3 of GPC 5 was sequenced with ABI Big Dye terminator chemistry.
The entire SLC15A1 gene was represented in one BAC clone sequence AL357553 and GPC5 in 6 BAC clone sequences.
Human Glypican5: GPC5