Example sentences for: gpcrs

How can you use “gpcrs” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In summary, GPCRs have an array of potential regulatory binding sites, or potential drug targets.

  • Furthermore, since some GPCRs can modulate MAP kinase activity, MAP kinase regulation of GPCR function may then serve as a form of negative feedback control in much the same way that protein kinase A, protein kinase C and the G protein-coupled receptor kinases (GRKs) regulate GPCRs.

  • What is the cellular function of sα i2 ? The ability of βγ to promote PM localization of sα i2 raises the possibility that endogenous sα i2 is in fact localized to PM where it can interact with GPCRs and effectors.

  • These results, taken together, suggest that GPCRs and RTKs can act as independent regulators of MAP kinase cascades, although interactions between the two receptor types may exist in certain cases.

  • Third, even though βγ can promote PM localization of sα i2 in the overexpression system described here, sα i2 remains less stable than α i2 (Figure 9), suggesting that such instability may also impair productive interactions with GPCRs.


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