Words similar to gpcrs

Example sentences for: gpcrs

How can you use “gpcrs” in a sentence? Here are some example sentences to help you improve your vocabulary:

Thus, we propose a variation of the classic 'ternary complex model' (Figure 8), a decades-old paradigm that has provided the foundation for describing ligand induced conformational changes of GPCRs [ 31 ] .
According to our analysis, homeobox proteins are involved in the regulation of or are regulated by many protein families such as GPCRs, ion channels, tyrosine phosphatases, nuclear hormone receptors, and protein kinases.
It was originally thought that GPCRs and tyrosine kinase receptors functioned independently to mediate different signaling events, but it has become clear in recent years that some functions and signaling pathways are shared (for reviews, see Marinissen and Gutkind, 2001 [ 1 ] ; Luttrell, 2002 [ 2 ] ; and van Biesen et al.
These data suggest that the tyrosine phosphorylation of GPCRs may allow them to signal ERKs in the absence of RTK or FAK phosphorylation by acting as their own scaffolds.
To interpret the results of the competition binding studies, we assume that the mutation in Smo act, like those in constitutively activate mutants of other GPCRs [ 29 ] , indirectly influences ligand binding by creating a change in the normal equilibrium between the different conformations of Smo.