Example sentences for: gpcrs

How can you use “gpcrs” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • How does Smo compare with other GPCRs with regard to the properties described above?

  • For example, ERK activation by GPCRs is predominantly a Ras-dependent event, one that utilizes many of the upstream protein intermediates (i.e.

  • In this report, we questioned whether the EGFR acts as a surrogate scaffold during ERK activation through the δ-OR, as it appears to do for several other GPCRs [ 7 ] . To act as a surrogate-binding site for complex formation, the literature states that this protein must first become tyrosine-phosphorylated [ 7 ] . Tyrosine phosphorylation of the EGFR is apparent after agonist stimulation of the α 2 -AR (COS-7), β 2 -AR (COS-7), insulin-like growth factor (IGF-1; COS-7), substance P, and the lysophosphatidic acid receptor (LPAR) [ 7 ] . In addition, each of the aforementioned ligands also increases ERK phosphorylation when the proper receptor is expressed in these cell lines.

  • And, he says, GPCRs could also be involved in these modalities.

  • According to our analysis, homeobox proteins are involved in the regulation of or are regulated by many protein families such as GPCRs, ion channels, tyrosine phosphatases, nuclear hormone receptors, and protein kinases.


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