Words similar to gonadotropin
Example sentences for: gonadotropin
How can you use “gonadotropin” in a sentence? Here are some example sentences to help you improve your vocabulary:
Male and non-pregnant, non-lactating female outpatients were eligible for study enrollment if they were at least 18 years of age; had HIV-1 infection documented by HIV-1 antibody enzyme-linked immunosorbent assay (ELISA) and confirmed by Western blot test, positive HIV-1 culture, positive HIV-1 serum antigen, or plasma viremia; and CD4+ cell counts ≥ 50/mm 3. Women of childbearing potential had to have a negative serum β-human chorionic gonadotropin (HCG) pregnancy test at screening, and had to be willing to use an adequate method of contraception during the study.
The pig granulosa cell line PGC-2 was obtained from Bruce Downey (McGill University) and maintained in culture in McCoy's modified 5A medium supplemented with 10% FBS, as described previously in detail [ 19 ] . PGC-2 cells have been well-characterized with respect to steroidogenic capability, cAMP response, and gonadotropin insensitivity [ 19 ] . Here, PGC-2 were seeded at a density of approximately 5 × 10 5cells/ml of serum-containing medium in 24-well tissue culture plates.
They were co-expressed with the luteinizing hormone (LH) receptor in HEK 293 cells and cAMP accumulation was measured in both the presence and absence of the LH receptor agonist, human chorionic gonadotropin (hCG).
Yet, elevated maternal mid-trimester chorionic gonadotropin is associated with fetal cerebral blood flow redistribution and adverse perinatal outcome [ 63 ] . In addition, estrogens, which are known to cause a diminution of high LH levels in postmenopausal women, have been reported to be effective in the prevention and treatment of Alzheimer's disease [ 72 73 74 ] . Microglia belong among cells of the mononuclear phagocyte system [ 75 ] . Since CG increases secretion of a variety of cytokines by monocytes, and induces their inflammatory reaction and phagocytic activity [ 76 77 78 79 ] , high LH levels in aging individuals may also activate resident macrophages in the central nervous system and contribute to the development of Alzheimer's disease and other inflammation-mediated neurodegenerative diseases.
They are not secreted from cells, but remain trapped intracellularly [ 18 ] . In addition to various glycosylated LHR variants, western blotting also yielded a 170 kDa band representing an LHR dimer [ 19 ] . LH binds to LHR variants with different affinities, and highest affinity appears to be associated with the fully glycosylated receptor (~90 kDa) [ 19 ] . Chorionic gonadotropin (CG), which is important for corpus luteum (CL) rescue and maintenance of pregnancy, also binds to LHR, although with a 10-fold lower binding affinity compared with that of LH [ 20 ] .
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