Words similar to glutathione
Example sentences for: glutathione
How can you use “glutathione” in a sentence? Here are some example sentences to help you improve your vocabulary:
Antioxidant capacity in preterm infants is also compromised by relative deficiencies of selenium and taurine, as well as reduced ability to synthesize sufficient glutathione [ 26].
IL-8, MCP-1 and RANTES gene expression are regulated by the redox responsive transcription factor NF-κB [ 18 20 23 25 26 27 28 29 30 31 32 33 41 42 43 44 ] . The NF-κB signaling pathways have been shown to be differentially affected by antioxidants and glucocorticoid steroids [ 45 ] . To determine whether RSV and TNFα induction of chemokine expression might be mediated by different NF-κB signaling pathways we pretreated A549 cells with the glutathione precursor N-acetyl-L-cysteine (NAC) or the synthetic glucocorticoid dexamethasone (DEX).
Proteins were eluted using reduced glutathione elution buffer (50 mM Tris.Cl, pH 8.0, 20 mM reduced glutathione, 0.01% Nonidet P-40, 100 mM NaCl).
The prodrug TLK286 [γ-glutamyl-α-amino-β(2-ethyl-N,N,N,N-tetrakis(2-chloroethyl)phosphorodiamidate)-sulfonyl-propionyl-(R)-(-)phenylglycine] is activated by glutathione S-transferase (GST) P1-1 and to a lesser degree A1-1 and generates tetrakis chloroethyl alkylating moieties that can react with cellular nucleophiles.
The tripeptide glutathione and the thiol reductants glutaredoxin and thioredoxin are key to the restoration of thiols to their reduced state (SH) (Fernandes and Holmgren 2004).