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Example sentences for: gibbs
How can you use “gibbs” in a sentence? Here are some example sentences to help you improve your vocabulary:
The Gibbs motif was deemed to match a known factor if:
Additionally, hidden Markov model based searches using a multiple alignment of known members were run using the HMMER2 package [ 36 ] . The Gibbs sampling procedure, as implemented in the MACAW program was used to detect and evaluate statistically significant conserved motifs [ 37 ] . Multiple alignments were constructed using the T_Coffee program [ 38 ] , followed by manual correction based on the PSI-BLAST results.
We have tailored the Gibbs algorithm (see methods) to this problem by searching for only one site at a time, and then masking only the central 1-2 bases of each sequence motif found before iterating.
We also applied the Gibbs sampling algorithm for motif identification [ 27].
The Gibbs sampling procedure revealed the presence of seven conserved motifs, with a probability of chance occurrence less than 10 -14, in the search space comprising of the 70 or so proteins that were identified in the above searches as having this domain.