Example sentences for: fos

How can you use “fos” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These signaling pathways in turn, activate a variety of transcription factors including NF-kappaB (p50/p65), AP-1 (c-Fos/c-Jun), and CREB phosphorylation, which in turn coordinate the induction of many genes encoding inflammatory mediators.

  • BTBD1 and BTBD2 were isolated as 15 and 19 independent clones, respectively, and in two-hybrid assays they interacted as strongly as the control for strongly interacting proteins (c-Fos with c-Jun).

  • Thus, the analysis of the multiple risk factors in the FOS indicated an overall tendency of the beneficial and harmful effects of alcohol intake to cancel out.

  • • Fifteen and nineteen independent cDNA clones of BTBD1 and BTBD2, respectively, were isolated from two-hybrid screens and found to interact as strongly as c-Fos interacted with c-Jun in the two-hybrid assays.

  • The protein product of this gene is a member of the activating protein-1 (AP-1) family [ 19 ] , which upon binding to either c-fos or fos B protein form a complex that have high affinity to AP-1 binding concensus sequence [ 20 ] . A wide variety of chemicals, including growth factors, and tumor promotors increase the expression of this gene in various cell types [ 21 ] . Compared to untransfected keratinocytes, JunB-transfected cells grew more rapidly, and were highly invasive in an in vitro assay [ 22 ] . Therefore, the increased hepatic levels of junB gene, in mice treated with RU486, was expected to reflect an uncontrolled hepatocellular growth in these animals.


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