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Example sentences for: fosmids

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Orthologous regions of the D. melanogaster genome corresponding to sequenced fosmids were identified using default parameters of BLAT [ 78] against a database made up of the Release 3 sequences [ 9].
The lengths of fosmids sequenced for the eight candidate regions are shown in Table 1. Though we were able to obtain species-specific STSs for the D. willistoni twi gene, we were not able to obtain clones for this region from the D. willistoni fosmid library.
In general, our data indicate that the microsyntenic order of coding and non-coding sequences is highly conserved in the genus Drosophila at the scale of individual fosmids (approximately 40 kb).
In the 30 fosmids, we predict a total of 164 protein-coding genes in non-melanogaster species (53 in D. erecta , 41 in D. pseudoobscura , 39 in D. willistoni , 31 in D. littoralis ) that form orthologous clusters with 81 D. melanogaster genes.